| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5248041 | B | Selectivity ratio of IC50 for human recombinant his tagged HDAC1 to IC50 for human recombinant his tagged HDAC3 | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 2. | ALA5248042 | B | Inhibition of human recombinant his tagged HDAC3 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by spectrophotometer based analysis | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 3. | ALA5248043 | B | Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysis | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 4. | ALA5248044 | B | Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by spectrophotometer based analysis | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 5. | ALA5248045 | B | Inhibition of human HDAC2 | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 6. | ALA5248048 | B | Inhibition of human HDAC6 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA5248059 | B | Inhibition of human HDAC4 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA5248060 | B | Inhibition of human HDAC5 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA5248061 | B | Inhibition of human HDAC7 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA5248066 | B | Selectivity ratio of IC50 for human recombinant his tagged HDAC3 to IC50 for human HDAC2 | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA5248067 | A | Metabolic stability in mouse plasma assessed as half life | Mus musculus | 1 | cell-free format | Scientific Literature | ||
| 12. | ALA5248068 | A | Metabolic stability in human plasma assessed as half life | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 13. | ALA5248069 | A | Metabolic stability in mouse hepatocyte assessed as half life | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5248070 | A | Metabolic stability in human hepatocyte assessed as half life | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!