# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5239614 | Binding | Inhibition of GST-tagged bacterial beta-lactamase NMD-1 expressed in Escherichia coli BL21(DE3) using CCF2-FA as substrate by fluorescence assay | Bacteria | 21 | ALA5236617 | assay format | Scientific Literature | |
2. | ALA5239615 | Binding | Inhibition of GST-tagged bacterial beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) using CCF2-FA as substrate by fluorescence assay | Bacteria | 21 | ALA5236617 | assay format | Scientific Literature | |
3. | ALA5239616 | Binding | Inhibition of GST-tagged bacterial beta-lactamase VIM-1 expressed in Escherichia coli BL21(DE3) using CCF2-FA as substrate by fluorescence assay | Bacteria | 21 | ALA5236617 | assay format | Scientific Literature | |
4. | ALA5239617 | Functional | Potentiation of imipenem-induced antibacterial activity against NDM-1 expressing Escherichia coli assessed as imipenem MIC incubated for 22 to 24 hrs (Rvb = 32 ug/ml) | Escherichia coli | 10 | ALA5236617 | organism-based format | Scientific Literature | |
5. | ALA5239618 | Functional | Potentiation of imipenem-induced antibacterial activity against IMP-1 expressing Serratia marcescens assessed as imipenem MIC incubated for 22 to 24 hrs (Rvb = 16 ug/ml) | Serratia marcescens | 10 | ALA5236617 | organism-based format | Scientific Literature | |
6. | ALA5239619 | Functional | Potentiation of imipenem-induced antibacterial activity against VIM-1 expressing Klebsiella pneumoniae assessed as imipenem MIC incubated for 22 to 24 hrs (Rvb = 16 ug/ml) | Klebsiella pneumoniae | 10 | ALA5236617 | organism-based format | Scientific Literature | |
7. | ALA5239620 | Unassigned | Selectivity ratio of MITC50 for NDM-1 expressing Escherichia coli to IC50 for GST-tagged bacterial beta-lactamase NMD-1 | 10 | ALA5236617 | assay format | Scientific Literature | ||
8. | ALA5239621 | Unassigned | Selectivity ratio of MITC50 for IMP-1 expressing Serratia marcescens to IC50 for GST-tagged bacterial beta-lactamase IMP-1 | 10 | ALA5236617 | assay format | Scientific Literature | ||
9. | ALA5239622 | Unassigned | Selectivity ratio of MITC50 for VIM-1 expressing Klebsiella pneumoniae to IC50 for GST-tagged bacterial beta-lactamase VIM-1 | 9 | ALA5236617 | assay format | Scientific Literature |