# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5264781 | Functional | Cytotoxicity against human SK-MEL3 cells assessed as cell growth inhibition upto 10 uM measured after 48 hrs by Caspase-Glo reagent based assay | Homo sapiens | 8 | ALA5260844 | cell-based format | Scientific Literature | |
2. | ALA5264792 | Functional | Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition upto 10 uM measured after 48 hrs by Caspase-Glo reagent based assay | Homo sapiens | 11 | ALA5260844 | cell-based format | Scientific Literature | |
3. | ALA5264794 | Functional | Cytotoxicity against human A498 cells assessed as cell growth inhibition upto 10 uM measured after 48 hrs by Caspase-Glo reagent based assay | Homo sapiens | 42 | ALA5260844 | cell-based format | Scientific Literature | |
4. | ALA5264795 | Functional | Cytotoxicity against human HeLa cells assessed as cell growth inhibition measured after 48 hrs by Caspase-Glo reagent based assay | Homo sapiens | 42 | ALA5260844 | cell-based format | Scientific Literature | |
5. | ALA5264796 | Functional | Cytotoxicity against human IMR-90 cells assessed as cell growth inhibition upto 10 uM measured after 48 hrs by Caspase-Glo reagent based assay | Homo sapiens | 11 | ALA5260844 | cell-based format | Scientific Literature | |
6. | ALA5264802 | ADME | Microsomal stability in human liver microsomes assessed as parent compound remaining measured after 1 hr in presence of NADPH by UHPLC-MS analysis | Homo sapiens | 7 | ALA5260844 | microsome format | Scientific Literature | |
7. | ALA5264803 | ADME | Microsomal stability in mouse liver microsomes assessed as parent compound remaining at 1 uM measured after 1 hr in presence of NADPH by UHPLC-MS analysis | Mus musculus | 7 | ALA5260844 | microsome format | Scientific Literature | |
8. | ALA5264804 | ADME | Plasma protein binding in human incubated for 5 hrs by UPLC-MS method | Homo sapiens | 7 | ALA5260844 | cell-free format | Scientific Literature | |
9. | ALA5264805 | ADME | Plasma protein binding in mouse incubated for 5 hrs by UPLC-MS method | Mus musculus | 7 | ALA5260844 | cell-free format | Scientific Literature | |
10. | ALA5264806 | ADME | Stability in human plasma assessed as parent compound remaining after 5 hrs | Homo sapiens | 7 | ALA5260844 | cell-free format | Scientific Literature | |
11. | ALA5264807 | ADME | Stability in mouse plasma assessed as parent compound remaining after 5 hrs | Mus musculus | 7 | ALA5260844 | cell-free format | Scientific Literature |