# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5251212 | B | Inhibition of sucrase in rat small intestinal brush border membrane vesicles using sucrose as substrate incubated for 30 mins by glucose-oxidase method | Rattus norvegicus | 16 | ALA5247644 | cell membrane format | Scientific Literature | |
2. | ALA5251213 | B | Inhibition of maltase in rat small intestinal brush border membrane vesicles using maltose as substrate incubated for 30 mins by glucose-oxidase method | Rattus norvegicus | 16 | ALA5247644 | cell membrane format | Scientific Literature | |
3. | ALA5251214 | B | Binding affinity to maltase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using maltose as substrate incubated for 30 mins by glucose-oxidase method | Rattus norvegicus | 5 | ALA5247644 | cell membrane format | Scientific Literature | |
4. | ALA5251215 | B | Binding affinity to sucrase in rat small intestinal brush border membrane vesicles assessed as inhibition constant using sucrose as substrate incubated for 30 mins by glucose-oxidase method | Rattus norvegicus | 5 | ALA5247644 | cell membrane format | Scientific Literature | |
5. | ALA5251220 | F | Antihyperglycemic activity in overnight fasted ICR mouse assessed as decrease in blood glucose level at 10 mg/kg, IG administered via tube and measured after 15 mins by sucrose loading test relative to control | Mus musculus | 3 | ALA5247644 | organism-based format | Scientific Literature | |
6. | ALA5251221 | F | Antihyperglycemic activity in overnight fasted ICR mouse assessed as decrease in blood glucose level at 10 mg/kg, IG administered via tube and measured after 30 mins by sucrose loading test relative to control | Mus musculus | 3 | ALA5247644 | organism-based format | Scientific Literature | |
7. | ALA5251222 | F | Antihyperglycemic activity in overnight fasted ICR mouse assessed as decrease in blood glucose level at 10 mg/kg, IG administered via tube and measured after 60 mins by sucrose loading test relative to control | Mus musculus | 3 | ALA5247644 | organism-based format | Scientific Literature | |
8. | ALA5251223 | F | Antihyperglycemic activity in overnight fasted ICR mouse assessed as decrease in AUC of blood glucose level at 10 mg/kg, IG administered via tube and measured after 15 to 60 mins by sucrose loading test relative to control | Mus musculus | 3 | ALA5247644 | organism-based format | Scientific Literature | |
9. | ALA5251224 | F | Antihyperglycemic activity in overnight fasted ICR mouse assessed as decrease in blood glucose level at 1 mg/kg, IG administered via tube and measured after 15 mins by sucrose loading test relative to control | Mus musculus | 3 | ALA5247644 | organism-based format | Scientific Literature | |
10. | ALA5251225 | F | Antihyperglycemic activity in overnight fasted ICR mouse assessed as decrease in blood glucose level at 1 mg/kg, IG administered via tube and measured after 30 mins by sucrose loading test relative to control | Mus musculus | 3 | ALA5247644 | organism-based format | Scientific Literature | |
11. | ALA5251226 | F | Antihyperglycemic activity in overnight fasted ICR mouse assessed as decrease in blood glucose level at 1 mg/kg, IG administered via tube and measured after 60 mins by sucrose loading test relative to control | Mus musculus | 3 | ALA5247644 | organism-based format | Scientific Literature | |
12. | ALA5251227 | F | Antihyperglycemic activity in overnight fasted ICR mouse assessed as decrease in AUC of blood glucose level at 1 mg/kg, IG administered via tube and measured after 15 to 60 mins by sucrose loading test relative to control | Mus musculus | 3 | ALA5247644 | organism-based format | Scientific Literature | |
13. | ALA5251228 | F | Antihyperglycemic activity in fasted rat assessed as decrease in blood glucose level at 1 mg/kg measured after 15 mins by maltose loading test relative to control | Rattus norvegicus | 4 | ALA5247644 | organism-based format | Scientific Literature | |
14. | ALA5251229 | F | Antihyperglycemic activity in fasted rat assessed as decrease in blood glucose level at 1 mg/kg measured after 30 mins by maltose loading test relative to control | Rattus norvegicus | 4 | ALA5247644 | organism-based format | Scientific Literature | |
15. | ALA5251230 | F | Antihyperglycemic activity in fasted rat assessed as decrease in blood glucose level at 1 mg/kg measured after 60 mins by maltose loading test relative to control | Rattus norvegicus | 4 | ALA5247644 | organism-based format | Scientific Literature | |
16. | ALA5251231 | F | Antihyperglycemic activity in fasted rat assessed as decrease in AUC of blood glucose level at 1 mg/kg measured for 15 to 60 mins by maltose loading test relative to control | Rattus norvegicus | 4 | ALA5247644 | organism-based format | Scientific Literature | |
17. | ALA5251233 | B | Potency index, ratio of neoponkoranol IC50 to test compound IC50 for inhibition of maltase in rat small intestinal brush border membrane vesicles using maltose as substrate incubated for 30 mins by glucose-oxidase method | Rattus norvegicus | 3 | ALA5247644 | cell membrane format | Scientific Literature | |
18. | ALA5251236 | B | Competitive inhibition of sucrase in rat small intestinal brush border membrane vesicles using sucrose as substrate incubated for 30 mins by Lineweaver-Burk plot analysis | Rattus norvegicus | 2 | ALA5247644 | cell membrane format | Scientific Literature | |
19. | ALA5251237 | B | Competitive inhibition of maltase in rat small intestinal brush border membrane vesicles using maltose as substrate incubated for 30 mins by Lineweaver-Burk plot analysis | Rattus norvegicus | 2 | ALA5247644 | cell membrane format | Scientific Literature |