#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5260383	B	Inhibition of porcine PDHc E1-subunit assessed as DCPIP reduction at 250 uM preincubated for 30 mins followed by pyruvate addition using 50 uM ThDP as substrate by microplate reader analysis	Sus scrofa	32	ALA5257137	single protein format	Scientific Literature
2.	ALA5260384	B	Inhibition of Escherichia coli OGDHc E1 subunit assessed as DCPIP reduction at 250 uM preincubated for 60 mins followed by pyruvate addition using 50 uM ThDP as substrate by microplate reader analysis	Escherichia coli	32	ALA5257137	assay format	Scientific Literature
3.	ALA5260386	B	Inhibition of Aerococcus viridans pyruvate oxidase at 250 uM preincubated for 30 mins followed by pyruvate addition using 50 uM ThDP as substrate by microplate reader analysis	Aerococcus viridans	32	ALA5257137	assay format	Scientific Literature
4.	ALA5260401	F	Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum 3D7 infected in human erythrocyte assessed as inhibition of parasite proliferation in thiamine free medium by SYBR-Safe assay	Plasmodium falciparum	9	ALA5257137	organism-based format	Scientific Literature
5.	ALA5260402	F	Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum 3D7 infected in human erythrocyte assessed as inhibition of parasite proliferation in presence of 2.97uM thiamine by SYBR-Safe assay	Plasmodium falciparum	9	ALA5257137	organism-based format	Scientific Literature
6.	ALA5260403	F	Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum 3D7 infected in human erythrocyte assessed as inhibition of parasite proliferation in presence of 297uM thiamine by SYBR-Safe assay	Plasmodium falciparum	9	ALA5257137	organism-based format	Scientific Literature
7.	ALA5260404	T	Cytotoxicity against human HFF cells assessed as inhibition of cell proliferation incubated for 96 hrs by SYBR- Safe assay	Homo sapiens	9	ALA5257137	cell-based format	Scientific Literature
8.	ALA5260405	T	Selectivity index, ratio of IC50 for cytotoxicity against human HFF cells to antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum 3D7 infected in human erythrocyte assessed as inhibition of parasite proliferation in thiamine free medium		9	ALA5257137	cell-based format	Scientific Literature
9.	ALA5260408	B	Inhibition of porcine PDHc E1-subunit assessed as DCPIP reduction at 250 uM preincubated for 30 mins followed by pyruvate addition using 125 uM ThDP as substrate by microplate reader analysis	Sus scrofa	12	ALA5257137	single protein format	Scientific Literature
10.	ALA5260410	B	Inhibition of Escherichia coli OGDHc E1 subunit assessed as DCPIP reduction at 250 uM preincubated for 60 mins followed by pyruvate addition using 125 uM ThDP as substrate by microplate reader analysis	Escherichia coli	12	ALA5257137	assay format	Scientific Literature
11.	ALA5260411	B	Inhibition of Aerococcus viridans pyruvate oxidase at 250 uM preincubated for 30 mins followed by pyruvate addition using 125 uM ThDP as substrate by microplate reader analysis	Aerococcus viridans	12	ALA5257137	assay format	Scientific Literature