# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5228446 | F | Antileishmanial activity against Leishmania mexicana promastigote infected in mouse J774A.1 cells assessed as inhibition of intracellular amastigotes growth measured after 72 hrs by Renilla luciferase assay system | Leishmania mexicana | 34 | organism-based format | Scientific Literature | ||
2. | ALA5228447 | T | Cytotoxicity against mouse J774A.1 cells measured after 1 hr in dark by SYBR Green I assay | Mus musculus | 34 | cell-based format | Scientific Literature | ||
3. | ALA5228448 | T | Selectivity index, ratio of EC50 for mouse J774A.1 cells to EC50 for Leishmania mexicana promastigote infected in mouse J774A.1 cell | 34 | assay format | Scientific Literature | |||
4. | ALA5228454 | A | Metabolic stability in mouse liver microsomes assessed as half life measured upto 4 hrs by UPLC-MS analysis | Mus musculus | 18 | microsome format | Scientific Literature | ||
5. | ALA5228455 | A | Metabolic stability in mouse liver microsomes assessed as clearance measured upto 4 hrs by UPLC-MS analysis | Mus musculus | 18 | microsome format | Scientific Literature |