| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5258418 | B | Inhibition of CDK2/Cyclin E1 (unknown origin) assessed as inhibition of substrate peptide phosphorylation using eIF4E-binding protein 1 as peptide substrate incubated for 4 hrs in presence of ATP by Lance Ultra HTRF assay | Homo sapiens | 24 | protein complex format | Scientific Literature | ||
| 2. | ALA5258419 | B | Inhibition of CDK1/Cyclin A2 (unknown origin) assessed as inhibition of substrate peptide phosphorylation using eIF4E-binding protein 1 as peptide substrate incubated for 2 hrs in presence of ATP by Lance Ultra HTRF assay | Homo sapiens | 24 | assay format | Scientific Literature | ||
| 3. | ALA5258420 | B | Selectivity ratio of IC50 for inhibition of CDK1/Cyclin A2 (unknown origin) to IC50 for inhibition of CDK2/Cyclin E1 (unknown origin) | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 4. | ALA5258421 | F | Antiproliferative activity against human OVCAR-3 cells assessed as inhibition of cell proliferation incubated for 6 days by CyQUANT reagent assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 5. | ALA5258422 | A | Microsomal stability in human liver microsomes assessed as half life at 1 uM measured upto 45 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 5 | microsome format | Scientific Literature | ||
| 6. | ALA5258423 | A | Apparent permeability across apical to basolateral side in dog MDCK-MDR1 cells at 5 uM incubated for 90 mins by LC-MS/MS analysis | Canis lupus familiaris | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA5258424 | A | Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in dog MDCK-MDR1 cells at 5 uM incubated for 90 mins by LC-MS/MS analysis | Canis lupus familiaris | 4 | cell-based format | Scientific Literature |
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