| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5254722 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current amplitude at -80 mV holding potential under more potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 7 | ALA5252552 | cell-based format | Scientific Literature | |
| 2. | ALA5254723 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current amplitude at -80 mV holding potential under less potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 7 | ALA5252552 | cell-based format | Scientific Literature | |
| 3. | ALA5254724 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal current at -80 mV holding potential under more potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay relative to control | Rattus norvegicus | 7 | ALA5252552 | cell-based format | Scientific Literature | |
| 4. | ALA5254725 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal current under less potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay relative to control | Rattus norvegicus | 7 | ALA5252552 | cell-based format | Scientific Literature | |
| 5. | ALA5254741 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 1 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 9 | ALA5252552 | cell-based format | Scientific Literature | |
| 6. | ALA5254742 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 3 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 10 | ALA5252552 | cell-based format | Scientific Literature | |
| 7. | ALA5254743 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 10 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 10 | ALA5252552 | cell-based format | Scientific Literature | |
| 8. | ALA5254744 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 30 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 10 | ALA5252552 | cell-based format | Scientific Literature | |
| 9. | ALA5254745 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 100 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 10 | ALA5252552 | cell-based format | Scientific Literature | |
| 10. | ALA5254746 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 300 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 10 | ALA5252552 | cell-based format | Scientific Literature | |
| 11. | ALA5254747 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 1 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 10 | ALA5252552 | cell-based format | Scientific Literature | |
| 12. | ALA5254748 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 3 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 10 | ALA5252552 | cell-based format | Scientific Literature | |
| 13. | ALA5254749 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 10 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 10 | ALA5252552 | cell-based format | Scientific Literature | |
| 14. | ALA5254750 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 30 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 10 | ALA5252552 | cell-based format | Scientific Literature | |
| 15. | ALA5254760 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 30 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 5 | ALA5252552 | cell-based format | Scientific Literature | |
| 16. | ALA5254789 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 30 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 4 | ALA5252552 | cell-based format | Scientific Literature | |
| 17. | ALA5254790 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 100 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 4 | ALA5252552 | cell-based format | Scientific Literature | |
| 18. | ALA5254791 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 300 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 4 | ALA5252552 | cell-based format | Scientific Literature | |
| 19. | ALA5254795 | B | Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 30 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 5 | ALA5252552 | cell-based format | Scientific Literature |
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