| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5227826 | B | Induction of GNMT in human H7GPL cells assessed as fold increase in promoter-driven luciferase reporter expression at 10 uM measured after 24 hrs by luminescence assay relative to control | Homo sapiens | 29 | ALA5226313 | cell-based format | Scientific Literature | |
| 2. | ALA5227833 | B | Induction of GNMT in human H7GPL cells assessed as fold increase in promoter-driven luciferase reporter expression at 2.5 uM measured after 24 hrs by luminescence assay relative to control | Homo sapiens | 26 | ALA5226313 | cell-based format | Scientific Literature | |
| 3. | ALA5227834 | F | Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth incubated for 72 hrs by Alamar blue assay | Homo sapiens | 1 | ALA5226313 | cell-based format | Scientific Literature | |
| 4. | ALA5227835 | F | Antiproliferative activity against human Hep3B cells assessed as inhibition of cell growth incubated for 72 hrs by Alamar blue assay | Homo sapiens | 1 | ALA5226313 | cell-based format | Scientific Literature | |
| 5. | ALA5227836 | F | Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by Alamar blue assay | Homo sapiens | 1 | ALA5226313 | cell-based format | Scientific Literature | |
| 6. | ALA5227837 | F | Inhibition of colony formation in human HepG2 cells after 10 days by crystal violet staining based assay | Homo sapiens | 1 | ALA5226313 | cell-based format | Scientific Literature | |
| 7. | ALA5227838 | F | Inhibition of colony formation in human Huh-7 cells after 10 days by crystal violet staining based assay | Homo sapiens | 1 | ALA5226313 | cell-based format | Scientific Literature | |
| 8. | ALA5227839 | F | Antitumor activity against human Huh-7 cells xenografted in mouse tumor model assessed as reduction in tumor volume at 10 to 25 mg/kg, po treated for 30 days | Homo sapiens | 1 | ALA5226313 | organism-based format | Scientific Literature | |
| 9. | ALA5227840 | T | Toxicity in NOD-SCID mouse assessed as survival at 10 to 25 mg/kg, po treated for 30 days | Mus musculus | 1 | ALA5226313 | organism-based format | Scientific Literature | |
| 10. | ALA5227841 | T | Toxicity in NOD-SCID mouse assessed as body weight at 10 to 25 mg/kg, po treated for 30 days | Mus musculus | 1 | ALA5226313 | organism-based format | Scientific Literature | |
| 11. | ALA5227842 | T | Toxicity in NOD-SCID mouse assessed as liver function at 10 to 25 mg/kg, po treated for 30 days | Mus musculus | 1 | ALA5226313 | organism-based format | Scientific Literature | |
| 12. | ALA5227843 | T | Toxicity in NOD-SCID mouse assessed as organ morphology at 10 to 25 mg/kg, po treated for 30 days | Mus musculus | 1 | ALA5226313 | organism-based format | Scientific Literature | |
| 13. | ALA5227844 | A | Drug uptake in NOD-SCID mouse assessed as organ morphology at 25 mg/kg, po treated for 30 days | Mus musculus | 1 | ALA5226313 | organism-based format | Scientific Literature | |
| 14. | ALA5227845 | F | Effect on HDAC1 protein expression in human Huh-7 cells at 0.6 to 10 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA5226313 | cell-based format | Scientific Literature | |
| 15. | ALA5227846 | F | Effect on HDAC2 protein expression in human Huh-7 cells at 0.6 to 10 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA5226313 | cell-based format | Scientific Literature | |
| 16. | ALA5227847 | F | Effect on HDAC1 protein expression in human HepG2 cells at 0.6 to 10 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA5226313 | cell-based format | Scientific Literature | |
| 17. | ALA5227848 | F | Effect on HDAC2 protein expression in human HepG2 cells at 0.6 to 10 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA5226313 | cell-based format | Scientific Literature | |
| 18. | ALA5227850 | F | Inhibition of MYC mRNA expression in human HepG2 cells at 0.6 to 10 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA5226313 | cell-based format | Scientific Literature | |
| 19. | ALA5227851 | F | Increase in p21 expression in human Huh-7 cells at 0.6 to 10 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA5226313 | cell-based format | Scientific Literature | |
| 20. | ALA5227852 | F | Reduction in MYC protein expression in tumor of mouse xenografted with human Huh-7 cells at 10 to 25 mg/kg, po treated for 30 days | Homo sapiens | 1 | ALA5226313 | organism-based format | Scientific Literature |
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