# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5257412 | B | Agonist activity at human Y1R expressed in myo-[2-3H]-inositol labelled African green monkey COS7 cells coexpressing chimeric Galphadelta6qi4myr protein assessed as accumulation of [2-3H]-IP after 1 hr by scintillation counting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA5257413 | B | Agonist activity at human Y2R expressed in myo-[2-3H]-inositol labelled African green monkey COS7 cells coexpressing chimeric Galphadelta6qi4myr protein assessed as accumulation of [2-3H]-IP after 1 hr by scintillation counting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA5257414 | B | Induction of internalization of C-terminal EYFP-tagged human Y1R transfected in HEK293 cells assessed as increase in fluorescence in intracellular vesicles at 100 nM measured after 1 hr by Hoechst33342 staining based live-cell microscopic analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA5257415 | B | Induction of internalization of C-terminal EYFP-tagged human Y2R transfected in HEK293 cells assessed as increase in fluorescence in intracellular vesicles at 100 nM measured after 1 hr by Hoechst33342 staining based live-cell microscopic analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA5257416 | F | Cytotoxicity against human MDA-MB-468 cells expressing Y1R assessed as reduction in cell viability treated for 8 hrs followed by culturing in proliferation medium for 72 hrs by resazurin assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
6. | ALA5257417 | F | Cytotoxicity against human MDA-MB-231 cells expressing Y1R assessed as reduction in cell viability treated for 8 hrs followed by culturing in proliferation medium for 72 hrs by resazurin assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
7. | ALA5257418 | F | Cytotoxicity against human T47D cells expressing Y1R assessed as reduction in cell viability treated for 8 hrs followed by culturing in proliferation medium for 72 hrs by resazurin assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
8. | ALA5257419 | F | Cytotoxicity against human MDA-MB-468 cells expressing Y1R assessed as reduction in cell viability at 25 uM treated for 8 hrs followed by culturing in proliferation medium for 72 hrs in presence of 10 equiv hY1R agonist, [F7,P34]-NPY by resazurin assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA5257422 | T | Cytotoxicity against human HEK293 cells assessed as cell viability at 2.5 to 10 uM treated for 8 hrs followed by culturing in proliferation medium for 72 hrs by resazurin assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
10. | ALA5257427 | F | Cytotoxicity against human T47D cells expressing Y1R assessed as reduction in cell viability at 50 uM treated for 8 hrs followed by culturing in proliferation medium for 72 hrs in presence of 10 equiv hY1R agonist, [F7,P34]-NPY by resazurin assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA5257430 | F | Cytotoxicity against human MDA-MB-231 cells expressing Y1R assessed as reduction in cell viability at 50 uM treated for 8 hrs followed by culturing in proliferation medium for 72 hrs in presence of 10 equiv hY1R agonist, [F7,P34]-NPY by resazurin assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA5257432 | B | Induction of internalization of C-terminal EYFP-tagged human Y1R transfected in HEK293 cells assessed as disappearance of green cell surface fluorescence at 100 nM measured after 1 hr by Hoechst33342 staining based live-cell microscopic analysis | Homo sapiens | 5 | cell-based format | Scientific Literature |