# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5236876 | B | Inhibition of GST-tagged TTBK1 (1 to 421) (unknown origin) using DNA Topoisomerase 2-alpha-Thr1342 as substrate incubated for 15 mins followed by ATP addition and further incubated for 120 mins by TR-FRET assay | Homo sapiens | 31 | single protein format | Scientific Literature | ||
2. | ALA5236877 | B | Inhibition of TTBK1 in human HEK293T cells incubated for 1 hrs by HTRF assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
3. | ALA5236878 | A | Apparent permeability across apical side to basolateral in dog MDCK-MDR1 cells | Canis lupus familiaris | 19 | cell-based format | Scientific Literature | ||
4. | ALA5236879 | A | Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in dog MDCK-MDR1 cells | Canis lupus familiaris | 24 | cell-based format | Scientific Literature | ||
5. | ALA5236880 | A | Intrinsic clearance in human liver microsomes at 1 uM incubated upto 40 mins | Homo sapiens | 13 | microsome format | Scientific Literature | ||
6. | ALA5236881 | A | Intrinsic clearance in rat liver microsomes at 1 uM incubated upto 40 mins | Rattus norvegicus | 13 | microsome format | Scientific Literature | ||
7. | ALA5236883 | P | Stability of the compound at pH 7.4 by UHPLC-MS/MS analysis | 6 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA5236884 | P | Stability of the compound at pH 7.4 in presence of glutathione incubated upto 4 hrs by UHPLC-MS/MS analysis | 6 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA5236885 | T | Cytotoxicity against human HepG2 cells in glucose containing media incubated for 72 hrs by celltiter-glo luminescent cell viability assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
10. | ALA5236886 | T | Cytotoxicity against human HepG2 cells in galactose containing media incubated for 72 hrs by celltiter-glo luminescent cell viability assay | Homo sapiens | 10 | cell-based format | Scientific Literature |