| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5248043 | B | Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysis | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 2. | ALA5248044 | B | Inhibition of human recombinant his tagged HDAC1 expressed in baculovirus expression system using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by spectrophotometer based analysis | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 3. | ALA5248045 | B | Inhibition of human HDAC2 | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 4. | ALA5248046 | B | Inhibition of human HDAC5 at 5 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA5248047 | B | Inhibition of human HDAC3 expressed in baculovirus infected insect cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by spectrophotometer based analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA5248048 | B | Inhibition of human HDAC6 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA5248049 | B | Inhibition of human HDAC4 at 5 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA5248050 | B | Inhibition of human HDAC7 at 5 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA5248051 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA5248052 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA5248053 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA5248054 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA5248055 | T | Genotoxicity in Salmonella typhimurium by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | assay format | Scientific Literature | ||
| 14. | ALA5248056 | T | Genotoxicity in Escherichia coli by Ames test | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 15. | ALA5248057 | A | Permeability of the compound in porcine brain endothelial cells by BBB assay | Sus scrofa | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5248058 | T | Inhibition of hERG potassium channel incubated for 4 hrs by fluorescence polarization assay | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 17. | ALA5248062 | T | Inhibition of hERG by patch clamp assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 18. | ALA5248063 | B | Inhibition of Nav1.5 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5248064 | B | Inhibition of Cav1.5 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA5248065 | A | Unbound fraction in human plasma | Homo sapiens | 1 | cell-free format | Scientific Literature |
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