# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5239394 | B | Inhibition of recombinant N-terminal GST-tagged human DLK (9 to 111 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylation using MKK4 and ATP as substrate incubated for 1.5 hrs by HTRF analysis | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
2. | ALA5239395 | B | Inhibition of recombinant N-terminal GST-tagged human LZK (9 to 114 residues) expressed in Sf21 cells assessed as reduction in substrate phosphorylation using MKK4 and ATP as substrate incubated for 1.5 hrs by HTRF analysis | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
3. | ALA5239396 | B | Inhibition of human DLK expressed in HEK cells assessed as reduction in phospho-c-Jun level preincubated for 45 mins followed by doxycycline stimulation and measured after 24 hrs by MSD ELISA | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
4. | ALA5239398 | A | Microsomal stability in human liver microsomes assessed as intrinsic clearance | Homo sapiens | 15 | microsome format | Scientific Literature | ||
5. | ALA5239399 | A | Efflux ratio of permeability across basolateral to apical side over apical to basolateral side in dog MDCK-MDR1 cells expressing human P-glycoprotein | Canis lupus familiaris | 13 | cell-based format | Scientific Literature |