# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5256558 | B | Inhibition of recombinant human furin using Pyr-Arg-Thr-Lys-Arg-AMC as substrate at 2.4 nM preincubated for 30 mins followed by substrate addition and measured for 40 mins by microplate reader method | Homo sapiens | 7 | single protein format | Scientific Literature | ||
2. | ALA5256559 | B | Inhibition of recombinant human furin using Pyr-Arg-Thr-Lys-Arg-AMC as substrate at 24 nM preincubated for 30 mins followed by substrate addition and measured for 40 mins by microplate reader method | Homo sapiens | 7 | single protein format | Scientific Literature | ||
3. | ALA5256560 | B | Inhibition of recombinant human furin using Pyr-Arg-Thr-Lys-Arg-AMC as substrate at 77 nM preincubated for 30 mins followed by substrate addition and measured for 40 mins by microplate reader method | Homo sapiens | 7 | single protein format | Scientific Literature | ||
4. | ALA5256561 | B | Inhibition of recombinant human furin using Pyr-Arg-Thr-Lys-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition and measured for 40 mins by microplate reader method | Homo sapiens | 4 | single protein format | Scientific Literature | ||
5. | ALA5256562 | B | Inhibition of recombinant human furin assessed as inhibition constant using Pyr-Arg-Thr-Lys-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition and measured for 40 mins by Cheng-Prusoff equation analysis | Homo sapiens | 5 | single protein format | Scientific Literature | ||
6. | ALA5256563 | B | Inhibition of human furin in human PANC-1 cells assessed as release of fluorescent AMC using Pyr-Arg-Thr-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by plate reader analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA5256564 | B | Inhibition of human furin in human PANC-1 cells assessed as release of fluorescent AMC using Pyr-Arg-Thr-Arg-AMC as substrate preincubated for 10 mins in presence of SFTI-1 then incubation with ligand for 30 mins followed by substrate addition by plate reader analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
8. | ALA5256565 | B | Inhibition of recombinant human Matriptase 1 ST14 catalytic domain using Boc-Gln-Ala-Arg-AMC as substrate at 3.85 to 385 nM preincubated for 30 mins followed by substrate addition and measured for 40 mins by microplate reader method | Homo sapiens | 4 | single protein format | Scientific Literature | ||
9. | ALA5256566 | B | Inhibition of recombinant human matriptase 2 using Boc-Gln-Ala-Arg-AMC as substrate at 3.85 to 385 nM preincubated for 30 mins followed by substrate addition and measured for 40 mins by microplate reader method | Homo sapiens | 4 | single protein format | Scientific Literature | ||
10. | ALA5256570 | A | Stability in human serum assessed as parent compound remaining at 1.54 mM and measured after 48 hrs by RP-HPLC analysis | Homo sapiens | 2 | cell-free format | Scientific Literature |