| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA651283 | F | Cytotoxicity against human breast cancer cells. | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 2. | ALA663728 | B | Binding affinity towards mutant dihydrofolate reductase (C59R+S108N+I164L DHFR) of Plasmodium falciparum | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
| 3. | ALA667200 | B | Binding affinity towards mutant dihydrofolate reductase (N51I+C59R+S108N DHFR) of Plasmodium falciparum | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
| 4. | ALA880697 | B | Binding affinity towards mutant dihydrofolate reductase (N51I+C59R+S108N+I164L DHFR) of Plasmodium falciparum | Plasmodium falciparum | 48 | single protein format | Scientific Literature | ||
| 5. | ALA668409 | B | Inhibition of the C59R+S108N mutant of dihydrofolate reductase (DHFR) | Plasmodium falciparum | 43 | single protein format | Scientific Literature | ||
| 6. | ALA668410 | B | Inhibition of the S108N mutant of dihydrofolate reductase (DHFR) | Plasmodium falciparum | 43 | single protein format | Scientific Literature | ||
| 7. | ALA668411 | B | Inhibition of the wild-type dihydrofolate reductase (DHFR) | Plasmodium falciparum | 43 | single protein format | Scientific Literature | ||
| 8. | ALA668417 | B | Inhibition of mutant C59R+S108N dihydrofolate reductase (DHFR) relative to Pyr | Plasmodium falciparum | 13 | single protein format | Scientific Literature | ||
| 9. | ALA668422 | B | Inhibition of mutant S108N dihydrofolate reductase (DHFR) relative to Pyr | Plasmodium falciparum | 13 | single protein format | Scientific Literature | ||
| 10. | ALA667611 | B | Inhibition of Plasmodium falciparum wild-type dihydrofolate reductase (DHFR) relative to Pyrimethamine. | Plasmodium falciparum | 21 | single protein format | Scientific Literature | ||
| 11. | ALA701605 | F | Cytotoxicity against human epidermoid carcinoma KB cell. | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 12. | ALA762995 | F | Antiplasmodial activity IC50 against Plasmodium falciparum K1CB1 DHFR double-mutant (C59R/S10) | Plasmodium falciparum | 43 | assay format | Scientific Literature | ||
| 13. | ALA767132 | F | In vitro antiplasmodial activity (IC50) against Plasmodium falciparum wtTM4/8.2 | Plasmodium falciparum | 43 | organism-based format | Scientific Literature | ||
| 14. | ALA760860 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase C59R+S108N/I164L (Csl-2) mutant | Plasmodium falciparum | 28 | assay format | Scientific Literature | ||
| 15. | ALA765484 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase CN51I/C59R/S108N/I164L (V1/S) mutant | Plasmodium falciparum | 28 | assay format | Scientific Literature | ||
| 16. | ALA765485 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase N51I/C59R/S108N (W2) | Plasmodium falciparum | 28 | assay format | Scientific Literature | ||
| 17. | ALA765486 | F | In vitro anti-plasmodial activity against Plasmodium falciparum dihydrofolate reductase wild type (TM4/8.2) | Plasmodium falciparum | 28 | assay format | Scientific Literature | ||
| 18. | ALA767962 | F | In vitro inhibition of Plasmodium falciparum HB3 (S108N) culture | Plasmodium falciparum | 3 | organism-based format | Scientific Literature | ||
| 19. | ALA767963 | F | In vitro inhibition of Plasmodium falciparum K1 (S108N + C59R) culture | Plasmodium falciparum | 3 | organism-based format | Scientific Literature | ||
| 20. | ALA811757 | B | Inhibitory activity against mutant Plasmodium falciparum DHFR-TS | Plasmodium falciparum | 2 | single protein format | Scientific Literature |
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