# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5255435 | Functional | Antiproliferative activity against human T24 cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 11 | ALA5252609 | cell-based format | Scientific Literature | |
2. | ALA5255436 | Functional | Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 11 | ALA5252609 | cell-based format | Scientific Literature | |
3. | ALA5255437 | Functional | Antiproliferative activity against human CNE-2 cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 11 | ALA5252609 | cell-based format | Scientific Literature | |
4. | ALA5255438 | Functional | Antiproliferative activity against human A2780 cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 11 | ALA5252609 | cell-based format | Scientific Literature | |
5. | ALA5255439 | Functional | Antitumor activity against human MGC-803 cells xenografted in nude mouse assessed as reduction in tumor volume growth rate at 4 mg/kg, ip administrated every other day for 21 days relative to control | Homo sapiens | 3 | ALA5252609 | organism-based format | Scientific Literature | |
6. | ALA5255440 | Functional | Antitumor activity against human MGC-803 cells xenografted in nude mouse assessed as reduction in tumor volume growth rate at 8 mg/kg, ip administrated every other day for 21 days relative to control | Homo sapiens | 2 | ALA5252609 | organism-based format | Scientific Literature | |
7. | ALA5255441 | Functional | Antitumor activity against human MGC-803 cells xenografted in nude mouse assessed as reduction in tumor weight at 4 mg/kg, ip administrated every other day for 21 days relative to control | Homo sapiens | 3 | ALA5252609 | organism-based format | Scientific Literature | |
8. | ALA5255442 | Functional | Antitumor activity against human MGC-803 cells xenografted in nude mouse assessed as reduction in tumor weight at 8 mg/kg, ip administrated every other day for 21 days relative to control | Homo sapiens | 2 | ALA5252609 | organism-based format | Scientific Literature | |
9. | ALA5255444 | Toxicity | Toxicity in nude mouse xenografted with human MGC-803 cells assessed as effect on body weight at 4 mg/kg, ip administrated every other day for 21 days | Mus musculus | 1 | ALA5252609 | organism-based format | Scientific Literature | |
10. | ALA5255446 | Functional | Toxicity in nude mouse xenografted with human MGC-803 cells assessed as morphological changes in liver at 8 mg/kg, ip administrated every other day for 21 days | Homo sapiens | 3 | ALA5252609 | organism-based format | Scientific Literature | |
11. | ALA5255450 | Binding | Binding affinity to pBR322 DNA (unknown origin) assessed as DNA intercalation at 20 to 100 uM by electrophoresis assay | Homo sapiens | 4 | ALA5252609 | assay format | Scientific Literature | |
12. | ALA5255451 | Binding | Binding affinity to pBR322 DNA (unknown origin) assessed as induced retardation of DNA migration at 20 to 100 uM by gel electrophoresis assay | Homo sapiens | 4 | ALA5252609 | assay format | Scientific Literature | |
13. | ALA5255452 | Binding | Inhibition of human DNA topoisomerase 1 assessed as reduction in pBR322 DNA relaxation at 10 to 20 uM by gel electrophoresis method | Homo sapiens | 2 | ALA5252609 | single protein format | Scientific Literature | |
14. | ALA5255455 | Functional | Induction of cell cycle arrest in human CNE-2 cells assessed as accumulation of cells at G1 phase at 0.5 uM measured after 48 hrs by flow cytometry analysis (Rvb= 73.18%) | Homo sapiens | 2 | ALA5252609 | cell-based format | Scientific Literature | |
15. | ALA5255456 | Functional | Induction of cell cycle arrest in human CNE-2 cells assessed as accumulation of cells at G2 phase at 0.5 uM measured after 48 hrs by flow cytometry analysis (Rvb= 6.99%) | Homo sapiens | 2 | ALA5252609 | cell-based format | Scientific Literature | |
16. | ALA5255457 | Functional | Induction of cell cycle arrest in human CNE-2 cells assessed as accumulation of cells at S phase at 0.5 uM measured after 48 hrs by flow cytometry analysis (Rvb= 19.83%) | Homo sapiens | 2 | ALA5252609 | cell-based format | Scientific Literature | |
17. | ALA5255458 | Functional | Induction of cell cycle arrest in human CNE-2 cells assessed as accumulation of cells at G1 phase at 1 uM measured after 48 hrs by flow cytometry analysis (Rvb= 73.18%) | Homo sapiens | 2 | ALA5252609 | cell-based format | Scientific Literature | |
18. | ALA5255459 | Functional | Induction of cell cycle arrest in human CNE-2 cells assessed as accumulation of cells at G2 phase at 1 uM measured after 48 hrs by flow cytometry analysis (Rvb= 6.99%) | Homo sapiens | 2 | ALA5252609 | cell-based format | Scientific Literature | |
19. | ALA5255460 | Functional | Induction of cell cycle arrest in human CNE-2 cells assessed as accumulation of cells at S phase at 1 uM measured after 48 hrs by flow cytometry analysis (Rvb= 19.83%) | Homo sapiens | 2 | ALA5252609 | cell-based format | Scientific Literature | |
20. | ALA5255461 | Functional | Induction of cell cycle arrest in human CNE-2 cells assessed as accumulation of cells at G1 phase at 2 uM measured after 48 hrs by flow cytometry analysis (Rvb= 73.18%) | Homo sapiens | 2 | ALA5252609 | cell-based format | Scientific Literature |