| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA668409 | B | Inhibition of the C59R+S108N mutant of dihydrofolate reductase (DHFR) | Plasmodium falciparum | 43 | single protein format | Scientific Literature | ||
| 2. | ALA668410 | B | Inhibition of the S108N mutant of dihydrofolate reductase (DHFR) | Plasmodium falciparum | 43 | single protein format | Scientific Literature | ||
| 3. | ALA668411 | B | Inhibition of the wild-type dihydrofolate reductase (DHFR) | Plasmodium falciparum | 43 | single protein format | Scientific Literature | ||
| 4. | ALA668417 | B | Inhibition of mutant C59R+S108N dihydrofolate reductase (DHFR) relative to Pyr | Plasmodium falciparum | 13 | single protein format | Scientific Literature | ||
| 5. | ALA668422 | B | Inhibition of mutant S108N dihydrofolate reductase (DHFR) relative to Pyr | Plasmodium falciparum | 13 | single protein format | Scientific Literature | ||
| 6. | ALA667611 | B | Inhibition of Plasmodium falciparum wild-type dihydrofolate reductase (DHFR) relative to Pyrimethamine. | Plasmodium falciparum | 21 | single protein format | Scientific Literature | ||
| 7. | ALA762995 | F | Antiplasmodial activity IC50 against Plasmodium falciparum K1CB1 DHFR double-mutant (C59R/S10) | Plasmodium falciparum | 43 | assay format | Scientific Literature | ||
| 8. | ALA767132 | F | In vitro antiplasmodial activity (IC50) against Plasmodium falciparum wtTM4/8.2 | Plasmodium falciparum | 43 | organism-based format | Scientific Literature | ||
| 9. | ALA849932 | B | Ratio of Inhibition of the C59R+S108N mutant of dihydrofolate reductase (DHFR) to inhibition of wild type dihydrofolate reductase. | Plasmodium falciparum | 40 | single protein format | Scientific Literature | ||
| 10. | ALA848232 | B | Ratio of Inhibition of the S108N mutant of dihydrofolate reductase (DHFR) to inhibition of wild type dihydrofolate reductase. | Plasmodium falciparum | 40 | single protein format | Scientific Literature | ||
| 11. | ALA849104 | F | IC50 ratio against Plasmodium falciparum K1CB1/TM4 | Plasmodium falciparum | 43 | organism-based format | Scientific Literature | ||
| 12. | ALA828776 | B | Inhibition constant against Plasmodium falciparum dihydrofolate reductase | Plasmodium falciparum | 52 | single protein format | Scientific Literature | ||
| 13. | ALA905732 | B | Inhibition of Mycobacterium tuberculosis DHFR expressed in Saccharomyces cerevisiae TB5 assessed as yeast growth inhibition after 3 days by radial spoke assay | Mycobacterium tuberculosis | 19 | assay format | Scientific Literature | ||
| 14. | ALA905733 | B | Inhibition of human DHFR expressed in Saccharomyces cerevisiae TB5 assessed as yeast growth inhibition after 3 days by radial spoke assay | Homo sapiens | 19 | assay format | Scientific Literature | ||
| 15. | ALA905734 | B | Inhibition of yeast DHFR expressed in Saccharomyces cerevisiae TB5 assessed as yeast growth inhibition by after 3 days by radial spoke assay | Saccharomyces cerevisiae | 19 | assay format | Scientific Literature |
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