# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5240621 | B | Displacement of [3H]-spiroperidol from rat D2L receptor expressed in HEK293 cells assessed as inhibition constant by Cheng-Prusoff equation analysis | Rattus norvegicus | 8 | cell-based format | Scientific Literature | ||
2. | ALA5240622 | B | Displacement of [3H]-spiroperidol from rat D3 receptor expressed in HEK293 cells assessed as inhibition constant by Cheng-Prusoff equation analysis | Rattus norvegicus | 9 | cell-based format | Scientific Literature | ||
3. | ALA5240624 | B | Selectivity ratio of Ki for displacement of [3H]-spiroperidol from rat D2L receptor expressed in HEK293 to Ki for displacement of [3H]-spiroperidol from rat D3 receptor expressed in HEK293 | Rattus norvegicus | 8 | assay format | Scientific Literature | ||
4. | ALA5240625 | B | Agonist activity at human D2 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding by Perkin elmer analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
5. | ALA5240626 | B | Agonist activity at human D2 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding by measuring maximum efficacy by Perkin elmer analysis relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
6. | ALA5240627 | B | Agonist activity at human D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding by Perkin elmer analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
7. | ALA5240628 | B | Agonist activity at human D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding by measuring maximum efficacy by Perkin elmer analysis relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
8. | ALA5240629 | B | Selectivity ratio of EC50 for agonist activity at human D2 receptor expressed in CHO cells to EC50 for agonist activity at human D3 receptor expressed in CHO cells | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
9. | ALA5240630 | B | Inhibition of alpha-Synuclein (unknown origin) aggregation assessed as reduction in alpha-Syn fibrillation by measuring fluorescence intensity at 172.9 uM incubated for 30 days by ThT fluorescence assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
10. | ALA5240631 | F | Cytotoxicity against rat PC-12 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature |