# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5238689 | A | Inhibition of CYP4Z1 in human HEK293T cells using Luciferin-BE as substrate at 10 uM incubated for 30 mins in presence of NADPH by luminescence based assay relative to control | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
2. | ALA5238690 | A | Inhibition of CYP4Z1 in human HEK293T cells using Luciferin-BE as substrate at 1 uM incubated for 30 mins in presence of NADPH by luminescence based assay relative to control | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
3. | ALA5238691 | A | Inhibition of CYP4Z1 in human HEK293T cells using Luciferin-BE as substrate incubated for 30 mins in presence of NADPH by luminescence based assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
4. | ALA5238692 | A | Inhibition of human recombinant CYP2D6 using Luciferin-ME EGE as substrate incubated for 30 mins in presence of NADPH by luminescence based assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
5. | ALA5238693 | A | Inhibition of human recombinant CYP2C9 using Luciferin CEE as substrate incubated for 30 mins in presence of NADPH by luminescence based assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
6. | ALA5238694 | A | Inhibition of human recombinant CYP3A4 using Luciferin-IPA as substrate incubated for 30 mins in presence of NADPH by luminescence based assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
7. | ALA5238695 | A | Inhibition of human recombinant CYP4F12 using Luciferin ME EGE as substrate incubated for 30 mins in presence of NADPH by luminescence based assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
8. | ALA5238696 | A | Inhibition of human recombinant CYP4F11 using Luciferin ME EGE as substrate incubated for 30 mins in presence of NADPH by luminescence based assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
9. | ALA5238697 | F | Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA5238698 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA5238699 | T | Toxicity in mouse assessed as body weight loss at 2000 mg/kg,po administered for 7 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
12. | ALA5238700 | A | Stability in mouse plasma assessed as half life at 40 uM incubated upto 5 hrs by LC-MS/MS analysis | Mus musculus | 1 | cell-free format | Scientific Literature | ||
13. | ALA5238701 | A | Stability in mouse liver microsomes assessed as half life at 1 uM incubated upto 60 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
14. | ALA5238702 | F | Inhibition of cell stemness in human MCF7 cells assessed as reduction in OCT4 expression at 0.8 to 51.2 uM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA5238703 | F | Inhibition of cell stemness in human MCF7 cells assessed as reduction in OCT3 expression at 0.8 to 51.2 uM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA5238704 | F | Inhibition of cell stemness in human MCF7 cells assessed as reduction in SOX2 expression at 0.8 to 51.2 uM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA5238705 | F | Inhibition of cell stemness in human MCF7 cells assessed as reduction in ALDH1A1 expression at 0.8 to 51.2 uM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA5238706 | F | Inhibition of cell stemness in human MCF7 cells assessed as reduction in P-gP expression at 0.8 to 51.2 uM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA5238707 | F | Inhibition of cell stemness in human MCF7 cells assessed as reduction in Nanog expression at 0.8 to 51.2 uM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA5238708 | F | Inhibition of cell stemness in human MDA-MB-231 cells assessed as reduction in OCT4 expression at 0.8 to 51.2 uM by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |