# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5255104 | F | Antimalarial activity against chloroquine sensitive Plasmodium falciparum 3D7 assessed as parasite growth inhibition incubated for 72 hrs by DAPI staining method | Plasmodium falciparum | 12 | organism-based format | Scientific Literature | ||
2. | ALA5255106 | F | Antimalarial activity against multidrug resistant Plasmodium falciparum Dd2 assessed as parasite growth inhibition incubated for 72 hrs by DAPI staining method | Plasmodium falciparum | 10 | organism-based format | Scientific Literature | ||
3. | ALA5255108 | T | Resistance index, ratio of IC50 for antimalarial activity against multidrug resistant Plasmodium falciparum Dd2 to IC50 for antimalarial activity against chloroquine sensitive Plasmodium falciparum 3D7 | 11 | assay format | Scientific Literature | |||
4. | ALA5255110 | T | Cytotoxicity against HEK293 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue dye based fluorescence assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
5. | ALA5255111 | T | Selectivity index, ratio of IC50 for cytotoxicity against HEK293 cells to IC50 for antimalarial activity against chloroquine sensitive Plasmodium falciparum 3D7 | 12 | cell-based format | Scientific Literature | |||
6. | ALA5255112 | T | Selectivity index, ratio of IC50 for cytotoxicity against HEK293 cells to IC50 for antimalarial activity against multidrug resistant Plasmodium falciparum Dd2 | 11 | cell-based format | Scientific Literature | |||
7. | ALA3854538 | F | Antimalarial activity against multi-drug-resistant Plasmodium falciparum K1 by microculture radioisotope technique | Plasmodium falciparum | 7 | assay format | Scientific Literature | ||
8. | ALA4150765 | F | Antiplasmodial activity against drug-sensitive Plasmodium falciparum 3D7 ring stage infected in human erythrocytes after 72 hrs by DAPI staining based method | Plasmodium falciparum | 13 | organism-based format | Scientific Literature | ||
9. | ALA4150766 | F | Antiplasmodial activity against 4-aminoquinoline/antifolates-resistant Plasmodium falciparum Dd2 ring stage infected in human erythrocytes after 72 hrs by DAPI staining based method | Plasmodium falciparum | 10 | organism-based format | Scientific Literature | ||
10. | ALA4150770 | A | Cytotoxicity against human HEK293 cells at 40 uM after 72 hrs by resazurin dye based fluorescence assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
11. | ALA4270462 | F | Antiviral activity against GFP-fused Human cytomegalovirus AD169 infected in HFF measured 7 days post infection | Human betaherpesvirus 5 | 9 | organism-based format | Scientific Literature | ||
12. | ALA4270466 | F | Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
13. | ALA4270467 | F | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
14. | ALA4270468 | F | Antiproliferative activity against human MDA-MB-361 cells after 72 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
15. | ALA4270469 | F | Antiproliferative activity against human T47D cells after 72 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
16. | ALA4270470 | F | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
17. | ALA4270471 | F | Antiproliferative activity against human SiHa cells after 72 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
18. | ALA4270472 | F | Antiproliferative activity against human C33A cells after 72 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
19. | ALA4303819 | F | Inhibition of cell viability relative to arbidol control (inhibition index > 1 indicates higher activity) measured by fluorescence (OD590nm) in Vero E6 cells infected with SARS-CoV-2 (strain BavPat1) at MOI 0.002 after 72hrs | Chlorocebus sabaeus | 1,518 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | ||
20. | ALA4321009 | F | Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature |