# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5255774 | B | Binding affinity to TYK2 JH2 domain (unknown origin) assessed as melting temperature at 10 uM by thermal shift assay | Homo sapiens | 22 | ALA5252617 | single protein format | Scientific Literature | |
2. | ALA5255775 | B | Binding affinity to TYK2 JH2 domain (unknown origin) assessed as melting temperature at 1 uM by thermal shift assay | Homo sapiens | 22 | ALA5252617 | single protein format | Scientific Literature | |
3. | ALA5255776 | B | Inhibition of TYK2 dependent IFNalpha-stimulated STAT3 phosphorylation in human Jurkat cells | Homo sapiens | 22 | ALA5252617 | cell-based format | Scientific Literature | |
4. | ALA5255777 | A | Stability in human liver microsomes assessed as parent compound remaining measured after 60 mins | Homo sapiens | 15 | ALA5252617 | microsome format | Scientific Literature | |
5. | ALA5255778 | A | Stability in mouse liver microsomes assessed as parent compound remaining measured after 60 mins | Mus musculus | 15 | ALA5252617 | microsome format | Scientific Literature |