# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5225729 | B | Antagonist activity at beta-galactosidase fused human GPR55 expressed in CHO cells assessed as inhibition of LPI-induced receptor activation by measuring beta-arrestin 2 recruitment incubated for 90 mins by PathHunter chemiluminescence based assay | Homo sapiens | 13 | ALA5223166 | cell-based format | Scientific Literature | |
2. | ALA5225732 | B | Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cell membranes assessed as inhibition constant incubated for 90 mins by liquid scintillation spectrometry analysis | Homo sapiens | 15 | ALA5223166 | cell membrane format | Scientific Literature | |
3. | ALA5225733 | B | Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK293 cell membranes assessed as inhibition constant incubated for 90 mins by liquid scintillation spectrometry analysis | Homo sapiens | 15 | ALA5223166 | cell membrane format | Scientific Literature | |
4. | ALA5225734 | B | Inverse agonist activity at human GPR55 expressed in HEK293 cells coexpressing serum response element assessed as reduction in MAPK/ERK signalling pathway by measuring SRE response incubated for 5 hrs in serum-free medium by luciferin based bioluminescence analysis | Homo sapiens | 1 | ALA5223166 | cell-based format | Scientific Literature | |
5. | ALA5225735 | B | Antagonist activity at human GPR55 expressed in HEK293 cells coexpressing serum response element assessed as inhibition of LPI-induced MAPK/ERK signalling pathway by measuring SRE response incubated for 5 hrs in serum-free medium by luciferin based bioluminescence analysis | Homo sapiens | 2 | ALA5223166 | cell-based format | Scientific Literature | |
6. | ALA5225736 | T | Cytotoxicity against CHO cells assessed as reduction in cell viability at upto 10 uM incubated for 24 hrs by XTT assay | Cricetulus griseus | 1 | ALA5223166 | cell-based format | Scientific Literature |