# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5240744 | Binding | Inhibition of PI3Kalpha (unknown origin) at 1 uM by kinase-glo luminescent assay relative to control | Homo sapiens | 18 | ALA5236659 | single protein format | Scientific Literature | |
2. | ALA5240745 | Binding | Inhibition of mTOR (unknown origin) at 1 uM by kinase-glo luminescent assay relative to control | Homo sapiens | 18 | ALA5236659 | single protein format | Scientific Literature | |
3. | ALA5240746 | Binding | Inhibition of PI3Kalpha (unknown origin) by kinase-glo luminescent assay | Homo sapiens | 18 | ALA5236659 | single protein format | Scientific Literature | |
4. | ALA5240747 | Binding | Inhibition of mTOR (unknown origin) by kinase-glo luminescent assay | Homo sapiens | 18 | ALA5236659 | single protein format | Scientific Literature | |
5. | ALA5240748 | Binding | Selectivity index, ratio of IC50 for inhibition of PI3Kalpha (unknown origin) to IC50 for inhibition of mTOR (unknown origin) by kinase glo luminescent assay | Homo sapiens | 9 | ALA5236659 | assay format | Scientific Literature | |
6. | ALA5240749 | Binding | Inhibition of KDR (unknown origin) at 1 uM by kinase-glo luminescent assay relative to control | Homo sapiens | 4 | ALA5236659 | single protein format | Scientific Literature | |
7. | ALA5240750 | Binding | Inhibition of MET (unknown origin) at 1 uM by kinase-glo luminescent assay relative to control | Homo sapiens | 4 | ALA5236659 | single protein format | Scientific Literature | |
8. | ALA5240751 | Binding | Inhibition of AKT1 (unknown origin) at 1 uM by kinase-glo luminescent assay relative to control | Homo sapiens | 4 | ALA5236659 | single protein format | Scientific Literature | |
9. | ALA5240752 | Binding | Inhibition of EGFR (unknown origin) at 1 uM by kinase-glo luminescent assay relative to control | Homo sapiens | 4 | ALA5236659 | single protein format | Scientific Literature | |
10. | ALA5240753 | Functional | Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA5236659 | cell-based format | Scientific Literature | |
11. | ALA5240754 | Functional | Antiproliferative activity against human OVCAR-2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA5236659 | cell-based format | Scientific Literature | |
12. | ALA5240755 | Functional | Antiproliferative activity against human U-87 MG cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA5236659 | cell-based format | Scientific Literature | |
13. | ALA5240756 | Functional | Selectivity ratio of IC50 for antiproliferative activity against human MCF7 cells to IC50 for antiproliferative activity against human U-87 MG cells | Homo sapiens | 12 | ALA5236659 | cell-based format | Scientific Literature | |
14. | ALA5240757 | Functional | Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA5236659 | cell-based format | Scientific Literature | |
15. | ALA5240758 | Functional | Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA5236659 | cell-based format | Scientific Literature | |
16. | ALA5240759 | Functional | Antiproliferative activity against human NCI-H2228 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA5236659 | cell-based format | Scientific Literature | |
17. | ALA5240760 | Functional | Antiproliferative activity against human NCI-H1975 cells overexpressing EGFR L858R/T790M mutant assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA5236659 | cell-based format | Scientific Literature | |
18. | ALA5240761 | Functional | Selectivity ratio of IC50 for antiproliferative activity against human A549 cells to IC50 for antiproliferative activity against human NCI-H1975 cells overexpressing EGFR L858R/T790M mutant | Homo sapiens | 14 | ALA5236659 | cell-based format | Scientific Literature | |
19. | ALA5240762 | Functional | Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA5236659 | cell-based format | Scientific Literature | |
20. | ALA5240763 | Functional | Antiproliferative activity against paclitaxel-resistant human HeLa cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA5236659 | cell-based format | Scientific Literature |