| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5252384 | B | Inhibition of human Nav1.7/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput electrophysiology system analysis | Homo sapiens | 26 | ALA5247677 | cell-based format | Scientific Literature | |
| 2. | ALA5252385 | B | Inhibition of mouse Nav1.7/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput electrophysiology system analysis | Mus musculus | 24 | ALA5247677 | cell-based format | Scientific Literature | |
| 3. | ALA5252386 | B | Selectivity ratio of IC50 for mouse Nav1.7/beta1/2 transfected in HEK293-A cells to IC50 for human Nav1.7/beta1/2 transfected in HEK293-A cells | 1 | ALA5247677 | cell-based format | Scientific Literature | ||
| 4. | ALA5252387 | T | Inhibition of human Nav1.1/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput electrophysiology system analysis | Homo sapiens | 22 | ALA5247677 | cell-based format | Scientific Literature | |
| 5. | ALA5252388 | T | Inhibition of human Nav1.5/beta1/2 transfected in HEK293-A cells assessed as inhibition of channel current incubated for 5.5 mins by high-throughput electrophysiology system analysis | Homo sapiens | 22 | ALA5247677 | cell-based format | Scientific Literature | |
| 6. | ALA5252389 | U | Selectivity ratio of IC50 for human Nav1.1/beta1/2 transfected in HEK293-A cells to IC50 for human Nav1.7/beta1/2 transfected in HEK293-A cells | 4 | ALA5247677 | cell-based format | Scientific Literature | ||
| 7. | ALA5252390 | U | Selectivity ratio of IC50 for human Nav1.5/beta1/2 transfected in HEK293-A cells to IC50 for human Nav1.7/beta1/2 transfected in HEK293-A cells | 3 | ALA5247677 | cell-based format | Scientific Literature | ||
| 8. | ALA5252391 | T | Inhibition of hERG at 100 uM | Homo sapiens | 19 | ALA5247677 | assay format | Scientific Literature | |
| 9. | ALA5252392 | P | 1-Octanol/PBS buffer distribution coefficient, log D of the compound at pH 7.4 by HPLC/LC-MS analysis | 19 | ALA5247677 | small-molecule physicochemical format | Scientific Literature | ||
| 10. | ALA5252393 | P | Aqueous thermodynamic solubility of the compound at pH 6.8 measured after 4 hrs by HPLC-UV analysis | 19 | ALA5247677 | small-molecule physicochemical format | Scientific Literature | ||
| 11. | ALA5252394 | A | Unbound fraction in mouse plasma | Mus musculus | 19 | ALA5247677 | cell-free format | Scientific Literature |
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