# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5237935 | B | Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
2. | ALA5237936 | B | Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as minimal acetylcholine response by calcium mobilisation assay relative to control | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
3. | ALA5237937 | P | Lipophilicity, logD of the compound at pH 7.4 | 16 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA5237938 | A | Intrinsic clearance in human | Homo sapiens | 12 | assay format | Scientific Literature | ||
5. | ALA5237939 | A | Intrinsic clearance in rat | Rattus norvegicus | 12 | assay format | Scientific Literature | ||
6. | ALA5237940 | B | Antagonist activity at rat muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
7. | ALA5237941 | B | Antagonist activity at rat muscarinic M5 receptor expressed in CHO cells assessed as minimal acetylcholine response by calcium mobilisation assay relative to control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
8. | ALA5237942 | B | Antagonist activity at human muscarinic M1 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA5237943 | B | Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as minimal acetylcholine response by calcium mobilisation assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA5237944 | B | Antagonist activity at human muscarinic M4 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA5237945 | A | Unbound fraction in rat plasma | Rattus norvegicus | 2 | cell-free format | Scientific Literature | ||
12. | ALA5237946 | A | Unbound fraction in human plasma | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
13. | ALA5237947 | A | Unbound fraction in rat brain | Rattus norvegicus | 2 | tissue-based format | Scientific Literature | ||
14. | ALA5237948 | A | Apparent permeability in MDCK-MDR1 cells | Canis lupus familiaris | 1 | cell-based format | Scientific Literature | ||
15. | ALA5237949 | A | Efflux ratio of permeability in MDCK-MDR1 cells expressing P-glycoprotein | Canis lupus familiaris | 1 | cell-based format | Scientific Literature |