| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5251029 | B | Inhibition of FGFR1 (unknown origin) at 100 nM using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA analysis relative to control | Homo sapiens | 15 | single protein format | Scientific Literature | ||
| 2. | ALA5251030 | B | Inhibition of FGFR1 (unknown origin) at 10 nM using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA analysis relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 3. | ALA5251031 | B | Inhibition of FGFR1 (unknown origin) at 1 nM using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA analysis relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 4. | ALA5251032 | B | Inhibition of FGFR2 (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 5. | ALA5251033 | B | Inhibition of FGFR3 (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 6. | ALA5251034 | B | Inhibition of FGFR4 (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA5251035 | F | Antiproliferative activity against human SNU-16 cells assessed as reduction in cell viability measured for 72 hrs | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 8. | ALA5251036 | P | Solubility of compound in PBS at pH 7.4 at 1 to 100 microg/ml by by laser nephelometry analysis | 13 | small-molecule physicochemical format | Scientific Literature | |||
| 9. | ALA5251037 | A | Stability in rat whole blood assessed as parent compound remaining measured upto 5 hrs by LC-MS/MS analysis | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
| 10. | ALA5251038 | A | Stability in rat whole blood assessed as parent compound remaining measured after 2 hrs by LC-MS/MS analysis | Rattus norvegicus | 2 | tissue-based format | Scientific Literature | ||
| 11. | ALA5251039 | P | GSH reactivity in PBS buffer assessed as percentage peak area ratio incubated for 24 hrs by LC-MS/MS analysis | 5 | small-molecule physicochemical format | Scientific Literature | |||
| 12. | ALA5251040 | B | Inhibition of FGFR signalling in human SNU-16 assessed as inhibition of pErk phosphorylation at 0.1 nM incubated for 2 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA5251041 | B | Inhibition of FGFR signalling in human SNU-16 assessed as inhibition of PLCgamma phosphorylation at 0.1 nM incubated for 2 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5251042 | B | Inhibition of FGFR phosphorylation in human SNU-16 cells at 5 nM measured after 12 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5251043 | B | Inhibition of FGFR phosphorylation in human SNU-16 cells at 5 nM measured after 24 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5251044 | T | Inhibition of hERG expressed in CHO cells at -80 mV holding potential by automated patch clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA5251045 | B | Inhibition of VEGFR1 (unknown origin) at 1 uM using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA5251046 | B | Inhibition of VEGFR2 (unknown origin) at 1 uM using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5251047 | B | Inhibition of human recombinant FGFR1 V561M mutant (456 to 765 residues) using GGEEEEYFELVKK as substrate incubated for 40 mins presence of [gamma-33P]-ATP by radiometric based scintillation counter assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA5251048 | B | Inhibition of human recombinant FGFR2 N549H mutant (456 to 770 residues) using GGEEEEYFELVKK as substrate incubated for 40 mins presence of [gamma-33P]-ATP by radiometric based scintillation counter assay | Homo sapiens | 1 | single protein format | Scientific Literature |
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