# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5246637 | B | Inhibition of IRAK4 (unknown origin) in presence of ATP by enzymatic assay | Homo sapiens | 35 | single protein format | Scientific Literature | ||
2. | ALA5246638 | B | Inhibition of IRAK4 (unknown origin) phosphorylation by cell based assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
3. | ALA5246639 | P | Lipophilicity, LogD at pH 7.4 of the compound by shake flask method | 35 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA5246640 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance | Homo sapiens | 27 | microsome format | Scientific Literature | ||
5. | ALA5246641 | A | Metabolic stability in human hepatocytes assessed as intrinsic clearance measured per 10^6 cells | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
6. | ALA5246642 | A | Apparent permeability across apical to basolateral side in human Caco-2 cells measured for 360 mins by liquid scintillation counting based analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
7. | ALA5246643 | A | Efflux ratio of apparent permeability basolateral to apical side over apical to basolateral side in human Caco-2 cells measured for 360 mins by liquid scintillation counting based analysis | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
8. | ALA5246644 | A | Metabolic stability in human cytosol assessed as intrinsic clearance | Homo sapiens | 8 | subcellular format | Scientific Literature | ||
9. | ALA5246671 | A | Clearance in human | Homo sapiens | 2 | assay format | Scientific Literature | ||
10. | ALA5246672 | A | Clearance in human assessed as liver blood flow | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
11. | ALA5246680 | B | Inhibition of FLT3 (unknown origin) in presence of 600 uM ATP | Homo sapiens | 6 | single protein format | Scientific Literature | ||
12. | ALA5246687 | B | Selectivity index, ratio of IC50 for inhibition of FLT3 (unknown origin) to IC50 for inhibition of IRAK4 (unknown origin) | Homo sapiens | 5 | assay format | Scientific Literature |