# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5230913 | B | Inhibition of human recombinant full length DDX3X helicase activity expressed in Escherichia coli using dsRNA as substrate measured after 40 mins by FRET assay | Homo sapiens | 13 | assay format | Scientific Literature | ||
2. | ALA5230914 | B | Inhibition of human recombinant full length DDX3X E256A mutant helicase activity using dsRNA as substrate measured after 40 mins by FRET assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
3. | ALA5230915 | B | Inhibition of human recombinant full length DDX3X R262A mutant helicase activity using dsRNA as substrate measured after 40 mins by FRET assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
4. | ALA5230916 | B | Selectivity ratio of ID50 for human recombinant full length DDX3X E256A mutant helicase activity to ID50 for human recombinant full length DDX3X helicase activity | Homo sapiens | 2 | assay format | Scientific Literature | ||
5. | ALA5230917 | B | Selectivity ratio of ID50 for human recombinant full length DDX3X R262A mutant helicase activity to ID50 for human recombinant full length DDX3X helicase activity | Homo sapiens | 2 | assay format | Scientific Literature | ||
6. | ALA5230918 | B | Inhibition of human DDX1 helicase activity | Homo sapiens | 2 | single protein format | Scientific Literature | ||
7. | ALA5230919 | B | Inhibition of Arabidopsis thaliana STRS2 helicase activity | Arabidopsis thaliana | 2 | assay format | Scientific Literature | ||
8. | ALA5230920 | B | Inhibition of Hepatitis C virus NSP 3 helicase activity | Hepatitis C virus | 2 | assay format | Scientific Literature | ||
9. | ALA5230921 | B | Selectivity ratio of ID50 for human DDX1 helicase activity to ID50 for human recombinant full length DDX3X helicase activity | Homo sapiens | 2 | assay format | Scientific Literature | ||
10. | ALA5230922 | B | Selectivity ratio of ID50 for Arabidopsis thaliana STRS2 helicase activity to ID50 for human recombinant full length DDX3X helicase activity | 2 | assay format | Scientific Literature | |||
11. | ALA5230923 | B | Selectivity ratio of ID50 for Hepatitis C virus NSP 3 helicase activity to ID50 for human recombinant full length DDX3X helicase activity | 2 | assay format | Scientific Literature | |||
12. | ALA5230924 | F | Antiviral activity against DENV2 New Guinea C strain infected in human Huh-7 cells measured after 72 hrs by immunodetection assay | dengue virus type 2 | 4 | organism-based format | Scientific Literature | ||
13. | ALA5230925 | F | Antiviral activity against WNV infected in human Huh-7 cells preincubated with cells for 1 hr and measured after 4 days by plaque reduction assay | West Nile virus | 4 | organism-based format | Scientific Literature | ||
14. | ALA5230926 | F | Cytotoxicity against human Huh-7 cells incubated for 72 hrs by Cell Titer-Glo luminescence assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
15. | ALA5230927 | F | Cytotoxicity against human Huh-7 cells incubated for 3 days by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature |