# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5260350 | B | Inhibition of human N-terminal His6-tagged recombinant full-length PLK1 expressed in baculovirus infected Sf9 cells incubated for 15 mins followed by ATP addition by ADP Glo luminescent assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
2. | ALA5260351 | B | Inhibition of human full length GST-tagged WEE1 expressed in insect cells incubated for 15 mins followed by ATP addition by ADP Glo luminescent assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
3. | ALA5260352 | B | Selectivity ratio, ratio of IC50 for human PLK1 to IC50 for human WEE1 by ADP Glo luminescent assay | Homo sapiens | 24 | assay format | Scientific Literature | ||
4. | ALA5260353 | B | Inhibition of WEE1 in human U2OS cells incubated for 1 hr by mesoscale discovery assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
5. | ALA5260354 | F | Antiproliferative activity against human A-427 cells assessed as cell growth inhibition measured after 7 days by alamar blue assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
6. | ALA5260355 | F | Antiproliferative activity against human NCI-H23 cells assessed as cell growth inhibition measured after 7 days by alamar blue assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
7. | ALA5260356 | T | Cytotoxicity against human Megakaryocyte cells assessed as inhibition of colony growth by measuring colony forming units | Homo sapiens | 29 | cell-based format | Scientific Literature |