#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5238191	B	Inhibition of SOS1/KRAS G13D mutant protein-protein interaction in human DLD-1 cells assessed as ERK1/2 phosphorylation measured after 1 hr by homogeneous time-resolved fluorescence (HTRF) method	Homo sapiens	51	ALA5236589	cell-based format	Scientific Literature
2.	ALA5238200	T	Toxicity in BALB/c mouse xenografted with human MIA PaCa-2 cells harboring KRAS G12C mutant assessed as change in body weight at 50 mg/kg, po once a day measured for 16 days	Mus musculus	5	ALA5236589	organism-based format	Scientific Literature
3.	ALA5238201	F	Antiproliferative activity against human MIA PaCa-2 cells assessed as cell viability measured after 72 hrs by MTT assay	Homo sapiens	1	ALA5236589	cell-based format	Scientific Literature
4.	ALA5238202	F	In vivo antitumor activity against human MIA PaCa-2 cells harboring KRAS G12C mutant xenografted in BALB/c mouse assessed as reduction in tumor volume at 50 mg/kg, po once a day measured for 16 days relative to BI-3406	Homo sapiens	1	ALA5236589	organism-based format	Scientific Literature
5.	ALA5238203	F	In vivo antitumor activity against human MIA PaCa-2 cells harboring KRAS G12C mutant xenografted in BALB/c mouse assessed as reduction in tumor volume at 50 mg/kg, po once a day measured for 16 days relative to control	Homo sapiens	4	ALA5236589	organism-based format	Scientific Literature
6.	ALA5238204	T	Toxicity in BALB/c mouse xenografted with human MIA PaCa-2 cells harboring KRAS G12C mutant assessed as mortality at 50 mg/kg, po once a day measured for 16 days	Mus musculus	4	ALA5236589	organism-based format	Scientific Literature
7.	ALA5238205	A	Metabolic stability in mouse liver microsomes assessed as half life in presence of NADPH by LC-MS/MS analysis	Mus musculus	2	ALA5236589	microsome format	Scientific Literature
8.	ALA5238206	A	Metabolic stability in mouse liver microsomes assessed as intrinsic clearance in presence of NADPH measured upto 60 mins by LC-MS/MS analysis	Mus musculus	2	ALA5236589	microsome format	Scientific Literature
9.	ALA5238207	A	Inhibition of CYP1A2 in human liver microsome suspension using phenacetin substrate incubated for 30 mins by LC/MS analysis	Homo sapiens	2	ALA5236589	microsome format	Scientific Literature
10.	ALA5238208	A	Inhibition of CYP2C8 in human liver microsome suspension using amodiaquine substrate incubated for 30 mins by LC/MS analysis	Homo sapiens	2	ALA5236589	microsome format	Scientific Literature
11.	ALA5238209	A	Inhibition of CYP2D6 in human liver microsome suspension using dextromethorphan substrate incubated for 30 mins by LC/MS analysis	Homo sapiens	2	ALA5236589	microsome format	Scientific Literature
12.	ALA5238210	A	Inhibition of CYP3A4 in human liver microsome suspension using midazolam substrate incubated for 30 mins by LC/MS analysis	Homo sapiens	2	ALA5236589	microsome format	Scientific Literature
13.	ALA5238211	A	Inhibition of CYP2C9 in human liver microsome suspension using diclofenac substrate incubated for 30 mins by LC/MS analysis	Homo sapiens	2	ALA5236589	microsome format	Scientific Literature
14.	ALA5238212	A	Inhibition of CYP2C19 in human liver microsome suspension using omeprazole substrate incubated for 30 mins by LC/MS analysis	Homo sapiens	2	ALA5236589	microsome format	Scientific Literature
15.	ALA5238213	T	Inhibition of human ERG channel expressed in HEK293 cells clamped at -80 mV stimulated +20 mV for 2 sec followed by repolarized to -50 mV for 5 secs by electrophysiological analysis	Homo sapiens	2	ALA5236589	cell-based format	Scientific Literature
16.	ALA5238214	A	Half life in ICR mouse at 20 mg/kg, po by LC-MS/MS analysis	Mus musculus	17	ALA5236589	organism-based format	Scientific Literature
17.	ALA5238215	A	Tmax in ICR mouse at 20 mg/kg, po by LC-MS/MS analysis	Mus musculus	17	ALA5236589	organism-based format	Scientific Literature
18.	ALA5238216	A	Cmax in ICR mouse at 20 mg/kg, po by LC-MS/MS analysis	Mus musculus	17	ALA5236589	organism-based format	Scientific Literature
19.	ALA5238217	A	AUC in ICR mouse at 20 mg/kg, po by LC-MS/MS analysis	Mus musculus	17	ALA5236589	organism-based format	Scientific Literature
20.	ALA5238218	A	MRT in ICR mouse at 20 mg/kg, po by LC-MS/MS analysis	Mus musculus	17	ALA5236589	organism-based format	Scientific Literature