# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5238906 | F | Antiviral activity against wild type HIV-1 NLRepRlucP373S infected in human MT2 cells assessed as inhibition of viral growth measured after 4 to 5 days by Dual luciferase reporter assay | Human immunodeficiency virus 1 | 28 | ALA5236606 | organism-based format | Scientific Literature | |
2. | ALA5238907 | F | Antiviral activity against wild type HIV-1 NLRepRlucP373S infected in human MT2 cells assessed as inhibition of viral growth measured after 4 to 5 days in presence of 10% FBS and 40% human serum supplemented with 27 mg/mL of human serum albumin by Dual luciferase reporter assay | Human immunodeficiency virus 1 | 25 | ALA5236606 | organism-based format | Scientific Literature | |
3. | ALA5238910 | F | Antiviral activity against wild type HIV-1 NLRepRlucP373S harboring T332S/V362I/prR41G mutant infected in human MT2 cells assessed as inhibition of viral growth measured after 4 to 5 days by Dual luciferase reporter assay | Human immunodeficiency virus 1 | 24 | ALA5236606 | organism-based format | Scientific Literature | |
4. | ALA5238913 | F | Fold resistance, ratio of EC50 for antiviral activity against wild type HIV-1 NLRepRlucP373S infected in human MT2 cells assessed as inhibition of viral growth in presence of 10% FBS and 40% human serum supplemented with 27mg/mL of human serum albumin to EC50 for antiviral activity against wild type HIV-1 NLRepRlucP373S infected in human MT2 cells assessed as inhibition of viral growth | Human immunodeficiency virus 1 | 25 | ALA5236606 | cell-based format | Scientific Literature | |
5. | ALA5238914 | T | Cytotoxicity against human MT2 cells assessed as reduction in cell viability | Homo sapiens | 25 | ALA5236606 | cell-based format | Scientific Literature |