# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5237935 | B | Antagonist activity at human muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assay | Homo sapiens | 18 | ALA5236576 | cell-based format | Scientific Literature | |
2. | ALA5237936 | B | Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as minimal acetylcholine response by calcium mobilisation assay relative to control | Homo sapiens | 15 | ALA5236576 | cell-based format | Scientific Literature | |
3. | ALA5237937 | P | Lipophilicity, logD of the compound at pH 7.4 | 16 | ALA5236576 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA5237938 | A | Intrinsic clearance in human | Homo sapiens | 12 | ALA5236576 | assay format | Scientific Literature | |
5. | ALA5237939 | A | Intrinsic clearance in rat | Rattus norvegicus | 12 | ALA5236576 | assay format | Scientific Literature | |
6. | ALA5237940 | B | Antagonist activity at rat muscarinic M5 receptor expressed in CHO cells in the presence of acetylcholine by calcium mobilisation assay | Rattus norvegicus | 2 | ALA5236576 | cell-based format | Scientific Literature | |
7. | ALA5237941 | B | Antagonist activity at rat muscarinic M5 receptor expressed in CHO cells assessed as minimal acetylcholine response by calcium mobilisation assay relative to control | Rattus norvegicus | 2 | ALA5236576 | cell-based format | Scientific Literature | |
8. | ALA5237945 | A | Unbound fraction in rat plasma | Rattus norvegicus | 2 | ALA5236576 | cell-free format | Scientific Literature | |
9. | ALA5237946 | A | Unbound fraction in human plasma | Homo sapiens | 2 | ALA5236576 | cell-free format | Scientific Literature | |
10. | ALA5237947 | A | Unbound fraction in rat brain | Rattus norvegicus | 2 | ALA5236576 | tissue-based format | Scientific Literature |