| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5228702 | B | Inhibition of FLT3 in human MV4-11 cells assessed as inhibition of STAT5 phosphorylation at Tyr694 residue incubated for 4 hrs by western blot analysis | Homo sapiens | 1 | ALA5226341 | cell-based format | Scientific Literature | |
| 2. | ALA5228703 | B | Inhibition of FLT3 in human MV4-11 cells assessed as inhibition of FLT3 phosphorylation at Tyr589/591 residue incubated for 4 hrs by western blot analysis | Homo sapiens | 1 | ALA5226341 | cell-based format | Scientific Literature | |
| 3. | ALA5228704 | F | Antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD-F691L mutant assessed as residual cell viability at 50 nM incubated for 72 hrs by CellTiterGlo luminescent assay | Mus musculus | 6 | ALA5226341 | cell-based format | Scientific Literature | |
| 4. | ALA5228706 | F | Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs by CellTiterGlo luminescent assay | Homo sapiens | 51 | ALA5226341 | cell-based format | Scientific Literature | |
| 5. | ALA5228707 | F | Antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD-F691L mutant assessed as reduction in cell viability incubated for 72 hrs by CellTiterGlo luminescent assay | Mus musculus | 13 | ALA5226341 | cell-based format | Scientific Literature | |
| 6. | ALA5228709 | F | Antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD-F691L mutant assessed as residual cell viability at 10 nM incubated for 72 hrs by CellTiterGlo luminescent assay | Mus musculus | 18 | ALA5226341 | cell-based format | Scientific Literature | |
| 7. | ALA5228710 | T | Antiproliferative activity against mouse BaF3 cells assessed as reduction in cell viability measured after 72 hrs by CellTiterGlo luminescent assay | Mus musculus | 2 | ALA5226341 | cell-based format | Scientific Literature | |
| 8. | ALA5228711 | F | Antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD mutant assessed as reduction in cell viability measured after 72 hrs by CellTiterGlo luminescent assay | Mus musculus | 2 | ALA5226341 | cell-based format | Scientific Literature | |
| 9. | ALA5228712 | F | Antiproliferative activity against mouse BaF3 cells harboring FLT3-TEL-D835V mutant assessed as reduction in cell viability measured after 72 hrs by CellTiterGlo luminescent assay | Mus musculus | 2 | ALA5226341 | cell-based format | Scientific Literature | |
| 10. | ALA5228713 | F | Antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD-D835V mutant assessed as reduction in cell viability measured after 72 hrs by CellTiterGlo luminescent assay | Mus musculus | 3 | ALA5226341 | cell-based format | Scientific Literature | |
| 11. | ALA5228714 | F | Antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD-Y842H mutant assessed as reduction in cell viability measured after 72 hrs by CellTiterGlo luminescent assay | Mus musculus | 2 | ALA5226341 | cell-based format | Scientific Literature | |
| 12. | ALA5228715 | F | Antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD-N676D mutant assessed as reduction in cell viability measured after 72 hrs by CellTiterGlo luminescent assay | Mus musculus | 2 | ALA5226341 | cell-based format | Scientific Literature | |
| 13. | ALA5228716 | F | Ratio of IC50 for antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD-F691L mutant to IC50 for antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD mutant | Mus musculus | 1 | ALA5226341 | cell-based format | Scientific Literature | |
| 14. | ALA5228717 | F | Ratio of IC50 for antiproliferative activity against mouse BaF3 cells harboring FLT3-TEL-D835V mutant to IC50 for antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD mutant | Mus musculus | 1 | ALA5226341 | cell-based format | Scientific Literature | |
| 15. | ALA5228718 | F | Ratio of IC50 for antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD-D835V mutant to IC50 for antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD mutant | Mus musculus | 1 | ALA5226341 | cell-based format | Scientific Literature | |
| 16. | ALA5228719 | F | Ratio of IC50 for antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD-Y842H mutant to IC50 for antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD mutant | Mus musculus | 1 | ALA5226341 | cell-based format | Scientific Literature | |
| 17. | ALA5228720 | F | Ratio of IC50 for antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD-N676D mutant to IC50 for antiproliferative activity against mouse BaF3 cells harboring FLT3-ITD mutant | Mus musculus | 1 | ALA5226341 | cell-based format | Scientific Literature | |
| 18. | ALA5228721 | T | Antiproliferative activity against mouse HCD-57 cells assessed as reduction in cell viability measured after 72 hrs by CellTiterGlo luminescent assay | Mus musculus | 1 | ALA5226341 | cell-based format | Scientific Literature | |
| 19. | ALA5228722 | F | Antiproliferative activity against mouse HCD-57 cells harboring FLT3-ITD mutant assessed as reduction in cell viability measured after 72 hrs by CellTiterGlo luminescent assay | Mus musculus | 1 | ALA5226341 | cell-based format | Scientific Literature | |
| 20. | ALA5228723 | F | Antiproliferative activity against mouse HCD-57 cells harboring FLT3-D835Y mutant assessed as reduction in cell viability measured after 72 hrs by CellTiterGlo luminescent assay | Mus musculus | 1 | ALA5226341 | cell-based format | Scientific Literature |
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