# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5240319 | B | Binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells incubated for 24 hrs by fluorescence polarization assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
2. | ALA5240320 | B | Binding affinity to HSP90beta (unknown origin) | Homo sapiens | 42 | single protein format | Scientific Literature | ||
3. | ALA5240321 | B | Selectivity index, ratio of IC50 for binding affinity to HSP90beta (unknown origin) to IC50 for binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
4. | ALA5240322 | B | Binding affinity to Grp94 (unknown origin) incubated for 24 hrs by fluorescence polarization assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
5. | ALA5240323 | B | Binding affinity to Trap1 (unknown origin) incubated for 24 hrs by fluorescence polarization assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
6. | ALA5240324 | B | Selectivity index, ratio of IC50 for binding affinity to Grp94 (unknown origin) to IC50 for binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
7. | ALA5240325 | B | Selectivity index, ratio of IC50 for binding affinity to Trap1 (unknown origin) to IC50 for binding affinity to N-terminal 6His tagged human HSP90alpha (1 to 223 residues) expressed in Escherichia coli BL21 (DE3) cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA5240326 | F | Antiproliferative activity against human NCI-H522 cell assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
9. | ALA5240327 | F | Antiproliferative activity against human SK-OV-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
10. | ALA5240328 | F | Antiproliferative activity against human UO-31 cells assessed as inhibition of cell growth incubated for 72 hrs by MTS assay | Homo sapiens | 6 | cell-based format | Scientific Literature |