# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5237300 | B | Inhibition of full length N-terminal his6-tagged human CH24H (28 to 494 residues) expressed in Escherichia coli DH5alpha using [14C] cholesterol as substrate preincubated for 15 mins followed by substrate addition and measured after 5 min in presence of beta-NADPH | Homo sapiens | 30 | assay format | Scientific Literature | ||
2. | ALA5237301 | A | Inhibition of CYP3A4 (unknown origin) at 10 uM using testosterone as substrate incubated for 60 mins by LC-MS/MS analysis relative to control | Homo sapiens | 17 | single protein format | Scientific Literature | ||
3. | ALA5237302 | A | Metabolic stability in human liver microsome assessed as clearance at 1 uM incubated for 15 to 30 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 6 | microsome format | Scientific Literature |