# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5236712 | B | Inhibition of recombinant p38alpha MAPK (unknown origin) at 10 uM preincubated for 10 mins followed by substrate addition and measured after 40 mins in the presence of ATP by ADP-Glo assay | Homo sapiens | 8 | ALA5236544 | single protein format | Scientific Literature | |
2. | ALA5236713 | B | Inhibition of TNF-alpha secretion in human THP-1 cells | Homo sapiens | 8 | ALA5236544 | cell-based format | Scientific Literature | |
3. | ALA5236714 | B | Inhibition of p38 (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA5236544 | protein format | Scientific Literature | |
4. | ALA5236715 | B | Inhibition of p38 (unknown origin) at 1.0 uM relative to control | Homo sapiens | 1 | ALA5236544 | protein format | Scientific Literature | |
5. | ALA5236716 | B | Inhibition of JNK (unknown origin) at 10 uM relative to control | Homo sapiens | 1 | ALA5236544 | protein format | Scientific Literature | |
6. | ALA5236717 | B | Inhibition of JNK (unknown origin) at 1.0 uM relative to control | Homo sapiens | 1 | ALA5236544 | protein format | Scientific Literature | |
7. | ALA5236718 | F | Antinflammatory activity in human THP-1 cells assessed as reduction of TNF-alpha at 10 uM relative to control | Homo sapiens | 1 | ALA5236544 | cell-based format | Scientific Literature | |
8. | ALA5236719 | F | Antinflammatory activity in human THP-1 cells assessed as reduction of TNF-alpha at 1.0 uM relative to control | Homo sapiens | 1 | ALA5236544 | cell-based format | Scientific Literature | |
9. | ALA5236720 | F | Neuroprotective activity against neurons (unknown origin) assessed as rescue by measuring cytokine level at 10 uM relative to control | Homo sapiens | 1 | ALA5236544 | cell-based format | Scientific Literature | |
10. | ALA5236721 | F | Neuroprotective activity against neurons (unknown origin) assessed as rescue by measuring cytokine level at 1.0 uM relative to control | Homo sapiens | 1 | ALA5236544 | cell-based format | Scientific Literature | |
11. | ALA5236722 | A | Drug concentration in mouse plasma at 10 mg/kg, iv administered once daily measured after 2 hrs | Mus musculus | 1 | ALA5236544 | organism-based format | Scientific Literature | |
12. | ALA5236723 | A | Drug concentration in mouse brain at 10 mg/kg, iv administered once daily measured after 2 hrs | Mus musculus | 1 | ALA5236544 | organism-based format | Scientific Literature |