# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5244406 | B | Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISA | Homo sapiens | 15 | single protein format | Scientific Literature | ||
2. | ALA5244407 | B | Inhibition of human JAK2 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISA | Homo sapiens | 15 | single protein format | Scientific Literature | ||
3. | ALA5244409 | A | Intrinsic clearance in Sprague-Dawley rat liver microsomes at 0.2 uM incubated for 45 mins in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 10 | microsome format | Scientific Literature | ||
4. | ALA5244410 | A | Time-dependent inhibition of CYP3A4 in human liver microsomes at 5 uM using midazolam as substrate preincubated for 0 to 30 mins followed by midazolam addition and measured after 20 mins by LC-MS/MS analysis relative to control | Homo sapiens | 13 | microsome format | Scientific Literature | ||
5. | ALA5244411 | A | Permeability of the compound in pH 6.5 incubated for 2 hrs by PAMPA based HPLC analysis | 15 | assay format | Scientific Literature |