# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5223843 | B | Partial agonist activity at human 5HT4E receptor expressed in CHO cells assessed as cAMP accumulation incubated for 4 hrs by luciferase reporter gene luminescence assay | Homo sapiens | 73 | ALA5223084 | cell-based format | Scientific Literature | |
2. | ALA5223844 | B | Partial agonist activity at human 5HT4E receptor expressed in CHO cells assessed as cAMP accumulation incubated for 4 hrs by luciferase reporter gene luminescence assay relative to control | Homo sapiens | 68 | ALA5223084 | cell-based format | Scientific Literature | |
3. | ALA5223845 | A | Drug metabolism in rat liver microsomes incubated for 30 mins in presence of NADPH by LC-MS/MS analysis | Rattus norvegicus | 26 | ALA5223084 | microsome format | Scientific Literature | |
4. | ALA5223846 | A | Drug metabolism in human liver microsomes incubated for 30 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 26 | ALA5223084 | microsome format | Scientific Literature | |
5. | ALA5223847 | T | Inhibition of hERG expressed in HEK293 cells at holding potential of -80 mV by whole cell patch clamp assay | Homo sapiens | 11 | ALA5223084 | cell-based format | Scientific Literature | |
6. | ALA5223848 | T | Inhibition of hERG expressed in HEK293 cells at holding potential of -80 mV by whole cell patch clamp assay relative to control | Homo sapiens | 11 | ALA5223084 | cell-based format | Scientific Literature | |
7. | ALA5223849 | A | Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 2 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Homo sapiens | 17 | ALA5223084 | microsome format | Scientific Literature | |
8. | ALA5223850 | A | Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 12 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Homo sapiens | 17 | ALA5223084 | microsome format | Scientific Literature |