| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5228272 | B | Inhibition of TNKS1 (unknown origin) using biotinylated NAD as substrate assessed as inhibition of autoPARsylation activity incubated for 1 hr by ELISA | Homo sapiens | 24 | single protein format | Scientific Literature | ||
| 2. | ALA5228273 | B | Modulation of Wnt/beta-catenin signaling pathway in human DLD-1 cells assessed as induction of AXIN2 accumulation incubated for 24 hrs by ELISA | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 3. | ALA5228274 | P | Solubility of compound at pH 7.4 | 24 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA5228276 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance per mg of protein by UPLC analysis | Homo sapiens | 23 | microsome format | Scientific Literature | ||
| 5. | ALA5228277 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance per mg of protein by UPLC analysis | Mus musculus | 24 | microsome format | Scientific Literature | ||
| 6. | ALA5228278 | B | Inhibition of TNKS2 (unknown origin) using biotinylated NAD as substrate assessed as inhibition of autoPARsylation activity incubated for 1 hr by ELISA | Homo sapiens | 23 | single protein format | Scientific Literature | ||
| 7. | ALA5228279 | B | Inhibition of PARP-1 (unknown origin) using biotinylated NAD and NAD as substrate assessed as inhibition of auto-PARsylation incubated for 150 mins by TR-FRET assay | Homo sapiens | 23 | single protein format | Scientific Literature | ||
| 8. | ALA5228286 | B | Binding affinity to recombinant human TNKS1 (1091 to 1327 residues) assessed as dissociation constant by ITC method | Homo sapiens | 3 | single protein format | Scientific Literature |
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