# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5232846 | F | Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 24 hrs by MTT assay | Homo sapiens | 19 | ALA5230164 | cell-based format | Scientific Literature | |
2. | ALA5232847 | F | Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 24 hrs by MTT assay | Homo sapiens | 19 | ALA5230164 | cell-based format | Scientific Literature | |
3. | ALA5232848 | F | Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 24 hrs by MTT assay | Homo sapiens | 19 | ALA5230164 | cell-based format | Scientific Literature | |
4. | ALA5232849 | B | Inhibition of porcine brain tubulin polymerization at 12 uM measured every 60 sec for 25 mins by fluorescence based assay | Sus scrofa | 1 | ALA5230164 | assay format | Scientific Literature | |
5. | ALA5232850 | B | Inhibition of porcine brain tubulin polymerization measured every 60 sec for 25 mins by fluorescence based assay | Sus scrofa | 1 | ALA5230164 | assay format | Scientific Literature | |
6. | ALA5232854 | B | Inhibition of tubulin polymerization in human MCF7 cells assessed as change in cell morphology at 0.35 to 1 uM incubated for 24 hrs by DAPI immunofluorescence based laser confocal microscopic analysis | Homo sapiens | 1 | ALA5230164 | cell-based format | Scientific Literature | |
7. | ALA5232855 | B | Inhibition of tubulin polymerization in human MCF7 cells assessed as disruption of microtubule network at 0.35 to 1 uM incubated for 24 hrs by DAPI immunofluorescence based laser confocal microscopic analysis | Homo sapiens | 1 | ALA5230164 | cell-based format | Scientific Literature | |
8. | ALA5232856 | B | Inhibition of tubulin polymerization in human MCF7 cells assessed as aggregation of microtubule network around the cell nuclei at 0.35 to 1 uM incubated for 24 hrs by DAPI immunofluorescence based laser confocal microscopic analysis | Homo sapiens | 1 | ALA5230164 | cell-based format | Scientific Literature | |
9. | ALA5232857 | F | Induction of apoptosis in human MCF7 cells assessed as viable cells at 0.35 uM incubated for 24 hrs by Annexin V-FITC and PI staining based flow cytometric analysis (Rvb = 94.8%) | Homo sapiens | 2 | ALA5230164 | cell-based format | Scientific Literature | |
10. | ALA5232858 | F | Induction of apoptosis in human MCF7 cells assessed as early apoptotic cells at 0.35 uM incubated for 24 hrs by Annexin V-FITC and PI staining based flow cytometric analysis (Rvb = 4.30%) | Homo sapiens | 2 | ALA5230164 | cell-based format | Scientific Literature | |
11. | ALA5232859 | F | Induction of apoptosis in human MCF7 cells assessed as late apoptotic cells at 0.35 uM incubated for 24 hrs by Annexin V-FITC and PI staining based flow cytometric analysis (Rvb = 0.81%) | Homo sapiens | 2 | ALA5230164 | cell-based format | Scientific Literature | |
12. | ALA5232860 | F | Induction of apoptosis in human MCF7 cells assessed as necrotic cells at 0.35 uM incubated for 24 hrs by Annexin V-FITC and PI staining based flow cytometric analysis (Rvb = 0.12%) | Homo sapiens | 2 | ALA5230164 | cell-based format | Scientific Literature | |
13. | ALA5232861 | F | Induction of apoptosis in human MCF7 cells assessed as viable cells at 1 uM incubated for 24 hrs by Annexin V-FITC and PI staining based flow cytometric analysis (Rvb = 94.8%) | Homo sapiens | 1 | ALA5230164 | cell-based format | Scientific Literature | |
14. | ALA5232862 | F | Induction of apoptosis in human MCF7 cells assessed as early apoptotic cells at 1 uM incubated for 24 hrs by Annexin V-FITC and PI staining based flow cytometric analysis (Rvb = 4.30%) | Homo sapiens | 1 | ALA5230164 | cell-based format | Scientific Literature | |
15. | ALA5232863 | F | Induction of apoptosis in human MCF7 cells assessed as late apoptotic cells at 1 uM incubated for 24 hrs by Annexin V-FITC and PI staining based flow cytometric analysis (Rvb = 0.81%) | Homo sapiens | 1 | ALA5230164 | cell-based format | Scientific Literature | |
16. | ALA5232864 | F | Induction of apoptosis in human MCF7 cells assessed as necrotic cells at 1 uM incubated for 24 hrs by Annexin V-FITC and PI staining based flow cytometric analysis (Rvb = 0.12%) | Homo sapiens | 1 | ALA5230164 | cell-based format | Scientific Literature | |
17. | ALA5232865 | F | Induction of cell cycle arrest in human MCF7 cells assessed as accumulation of cells at G2/M phase at 0.35 uM incubated for 24 hrs by PI staining based flow cytometric analysis (Rvb = 4.17%) | Homo sapiens | 2 | ALA5230164 | cell-based format | Scientific Literature | |
18. | ALA5232866 | F | Induction of cell cycle arrest in human MCF7 cells assessed as accumulation of cells at G2/M phase at 1 uM incubated for 24 hrs by PI staining based flow cytometric analysis (Rvb = 4.17%) | Homo sapiens | 1 | ALA5230164 | cell-based format | Scientific Literature | |
19. | ALA5232867 | T | Cytotoxicity against human L02 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Homo sapiens | 2 | ALA5230164 | cell-based format | Scientific Literature | |
20. | ALA5232868 | T | Cytotoxicity against human HEK293T cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay | Homo sapiens | 2 | ALA5230164 | cell-based format | Scientific Literature |