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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5236038 B Displacement of [125]IBNtxA from mouse MOR stably expressed in CHO cell membranes incubated for 90 mins Mus musculus 7 ALA5233277 cell membrane format Scientific Literature 2. ALA5236039 B Displacement of [125]IBNtxA from mouse KOR stably expressed in CHO cell membranes incubated for 90 mins Mus musculus 7 ALA5233277 cell membrane format Scientific Literature 3. ALA5236040 B Displacement of [125]IBNtxA from mouse DOR stably expressed in CHO cell membranes incubated for 90 mins Mus musculus 7 ALA5233277 cell membrane format Scientific Literature 4. ALA5236041 B Agonist activity at mouse MOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillation spectroscopy analysis Mus musculus 5 ALA5233277 cell membrane format Scientific Literature 5. ALA5236046 B Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding incubated for 60 mins by scintillation spectroscopy analysis Mus musculus 6 ALA5233277 cell membrane format Scientific Literature 6. ALA5236047 B Agonist activity at mouse KOR expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgammaS binding by measuring maximal efficacy incubated for 60 mins by scintillation spectroscopy analysis relative to U50,488H Mus musculus 5 ALA5233277 cell membrane format Scientific Literature 7. ALA5236048 B Antagonist activity at mouse DOR expressed in CHO cell membranes assessed as inhibition of DPDPE induced [35S]-GTPgammaS binding incubated for 60 mins by scintillation spectroscopy analysis Mus musculus 5 ALA5233277 cell membrane format Scientific Literature 8. ALA5236049 F Antinociceptive activity in sc dosed 129Sv6 mouse model assessed as peak effect measured at 15 mins by radiant heat tail flick assay Mus musculus 10 ALA5233277 organism-based format Scientific Literature 9. ALA5236133 F Antinociceptive activity in mouse Mus musculus 1 ALA5233277 organism-based format Scientific Literature 10. ALA5236134 T Toxicity in sc dosed C57BL/6J mouse assessed as lethality at 50 mg/kg, sc Mus musculus 1 ALA5233277 organism-based format Scientific Literature 11. ALA5236135 T Toxicity in sc dosed 129Sv6 mouse assessed as lethality Mus musculus 1 ALA5233277 organism-based format Scientific Literature 12. ALA5236136 T Toxicity in sc dosed CD1 mouse assessed as lethality Mus musculus 1 ALA5233277 organism-based format Scientific Literature 13. ALA5236137 T Toxicity in MOR knock out C57BL/6J mouse at 50 mg/kg, sc in presence of norbinaltorphimine Mus musculus 1 ALA5233277 organism-based format Scientific Literature 14. ALA5236138 T Toxicity in MOR knock out C57BL/6J mouse at 50 mg/kg, sc in presence of naltrindole Mus musculus 1 ALA5233277 organism-based format Scientific Literature 15. ALA5236139 T Toxicity in C57BL/6J mouse at 50 mg/kg, sc in presence of norbinaltorphimine Mus musculus 1 ALA5233277 organism-based format Scientific Literature 16. ALA5236140 T Toxicity in C57BL/6J mouse at 50 mg/kg, sc in presence of naltrindole Mus musculus 1 ALA5233277 organism-based format Scientific Literature 17. ALA5236141 T Toxicity in CD1 mouse assessed as fatality at 10 ug, IT Mus musculus 1 ALA5233277 assay format Scientific Literature 18. ALA5236142 T Toxicity in 129Sv6 mouse assessed as fatality at 10 ug, IT Mus musculus 1 ALA5233277 assay format Scientific Literature 19. ALA5236153 A Drug concentration in C57BL/6J mouse brain at 30 mg/kg, po measured after 24 hrs by LC-MS/MS analysis Mus musculus 2 ALA5233277 organism-based format Scientific Literature 20. ALA5236154 A Drug concentration in C57BL/6J mouse plasma at 30 mg/kg, po measured after 24 hrs by LC-MS/MS analysis Mus musculus 2 ALA5233277 organism-based format Scientific Literature