#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5242438	B	Inhibition of human MCT4 in human MDA-MB-231 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measured after 4 hrs by dialysis based UHPLC-ESI-Q-Orbitrap-MS analysis	Homo sapiens	73	ALA5241094	cell-based format	Scientific Literature
2.	ALA5242442	A	Metabolic stability in human liver microsomes assessed as intrinsic clearance measured per mg of protein	Homo sapiens	5	ALA5241094	microsome format	Scientific Literature
3.	ALA5242443	P	Solubility of compound in PBS buffer at pH 7.4 and measured after 24 hrs		5	ALA5241094	small-molecule physicochemical format	Scientific Literature
4.	ALA5242444	A	Efflux ratio of permeability in human Caco-2 cells	Homo sapiens	5	ALA5241094	cell-based format	Scientific Literature
5.	ALA5242445	A	Clearance in C57BL/6 mouse at 0.2 mg/kg, iv and measured after 2 hrs by HPLC-MS/MS analysis	Mus musculus	8	ALA5241094	organism-based format	Scientific Literature
6.	ALA5242446	A	Volume of distribution at steady state in C57BL/6 mouse at 0.2 mg/kg, iv and measured after 2 hrs by HPLC-MS/MS analysis	Mus musculus	8	ALA5241094	organism-based format	Scientific Literature
7.	ALA5242447	B	Binding affinity to full-length C-terminal GFP-tagged human MCT4 incubated for 1 hrs by fluorescence cross-correlation spectroscopy analysis	Homo sapiens	13	ALA5241094	single protein format	Scientific Literature
8.	ALA5242456	B	Inhibition of human MCT4 in human NCI-H358 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measured after 4 hrs by dialysis based UHPLC-ESI-Q-Orbitrap-MS analysis	Homo sapiens	1	ALA5241094	cell-based format	Scientific Literature
9.	ALA5242457	B	Inhibition of human MCT4 in human NCI-H441 cells assessed as inhibition of lactate efflux preincubated for 30 mins followed by D(+)glucose and measured after 4 hrs by dialysis based UHPLC-ESI-Q-Orbitrap-MS analysis	Homo sapiens	1	ALA5241094	cell-based format	Scientific Literature
10.	ALA5242460	A	Oral bioavailability in C57/BL6 mouse at 30 mg/kg administered as homogeneous suspension in 0.5% methocel/0.25% tween20 in 50 mM phosphate buffer (pH 7.4) and measured after 2 hrs by HPLC-MS/MS analysis	Mus musculus	1	ALA5241094	organism-based format	Scientific Literature
11.	ALA5242461	A	Free drug exposure in C57/BL6 mouse plasma assessed as time to exceeding cellular IC50 at 30 mg/kg,po administered as homogeneous suspension in 0.5% methocel/0.25% tween20 in 50 mM phosphate buffer (pH 7.4) by HPLC-MS/MS analysis	Mus musculus	1	ALA5241094	organism-based format	Scientific Literature
12.	ALA5242462	T	Toxicity in SCID mouse assessed as drug tolerability upto 200 mg/kg, po QD for 10 days	Mus musculus	2	ALA5241094	organism-based format	Scientific Literature
13.	ALA5242463	T	Toxicity in SCID mouse assessed as change in body weight upto 200 mg/kg, po QD for 10 days	Mus musculus	2	ALA5241094	organism-based format	Scientific Literature
14.	ALA5242464	F	Invivo inhibition of lactate efflux in human NCI-H358 cells expressing high MCT4 and low MCT1 xenografted in C57/BL6 mouse assessed as decrease in intracellular tumor lactate accumulation at 100 mg/kg,po BID and measured after 2 hrs by Dialysis method	Mus musculus	2	ALA5241094	organism-based format	Scientific Literature
15.	ALA5242465	F	Invivo inhibition of lactate efflux in human NCI-H441 cells expressing high MCT4 and low MCT1 xenografted in C57/BL6 mouse assessed as decrease in intracellular tumor lactate accumulation at 100 mg/kg,po BID and measured after 2 hrs by Dialysis method	Mus musculus	2	ALA5241094	organism-based format	Scientific Literature
16.	ALA5242466	F	Antitumor activity in human NCI-H358 cells expressing high MCT4 and low MCT1 xenografted in C57/BL6 mouse assessed as tumor growth inhibition at 100 mg/kg,po BID and measured after 2 hrs	Homo sapiens	2	ALA5241094	organism-based format	Scientific Literature
17.	ALA5242467	F	Antitumor activity in human NCI-H441 cells expressing high MCT4 and low MCT1 xenografted in C57/BL6 mouse assessed as tumor growth inhibition at 100 mg/kg,po BID and measured after 2 hrs	Homo sapiens	2	ALA5241094	organism-based format	Scientific Literature
18.	ALA5242468	F	Invivo inhibition of lactate efflux in human MDA-MB-231 cells expressing high MCT4 and no MCT1 xenografted in C57/BL6 mouse assessed as decrease in intracellular tumor lactate accumulation at 100 mg/kg,po BID and measured after 2 hrs by Dialysis method	Homo sapiens	2	ALA5241094	organism-based format	Scientific Literature
19.	ALA5242469	F	Antitumor activity in human MDA-MB-231 cells expressing high MCT4 and low MCT1 xenografted in C57/BL6 mouse assessed as tumor growth inhibition at 100 mg/kg,po BID and measured after 2 hrs	Homo sapiens	2	ALA5241094	organism-based format	Scientific Literature