| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5249644 | B | Inhibition of human glutaminyl cyclase using L-glutamine-7-amido-4-methylcoumarin as substrate incubated for 10 mins in presence of pyroglutamyl peptidase by fluorometry analysis | Homo sapiens | 35 | single protein format | Scientific Literature | ||
| 2. | ALA5249645 | T | Cytotoxicity against mouse HT-22 cells assessed as cell viability at 10 uM incubated for 18 hrs by MTT assay relative to control | Mus musculus | 16 | cell-based format | Scientific Literature | ||
| 3. | ALA5249646 | T | Inhibition of hERG at 10 uM by fluorescence polarization assay relative to control | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 4. | ALA5249648 | A | Effective permeability coefficient by PAMPA-BBB assay | 16 | assay format | Scientific Literature | |||
| 5. | ALA5249650 | F | Antialzheimer activity in human amyloid beta (3 to 40 residues) induced ICR mouse model assessed as inhibition of pyroglutamate form of amyloid-beta formation in brain at 10 mM, icv by sandwich ELISA relative to control | Mus musculus | 8 | organism-based format | Scientific Literature |
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