# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5244112 | B | Inhibition of PI3Kdelta (unknown origin) by ADP Glo luminescent assay | Homo sapiens | 25 | single protein format | Scientific Literature | ||
2. | ALA5244113 | B | Inhibition of PI3Kalpha (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
3. | ALA5244114 | B | Inhibition of PI3Kbeta (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
4. | ALA5244115 | B | Inhibition of PI3Kgamma (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
5. | ALA5244116 | F | Antiproliferative activity against human MOLM16 cells assessed as inhibition of cell growth | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA5244117 | F | Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA5244118 | F | Antiproliferative activity against human KG-1 cells assessed as inhibition of cell growth | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA5244119 | F | Antiproliferative activity against human EOL1 cells assessed as inhibition of cell growth | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
9. | ALA5244120 | F | Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
10. | ALA5244121 | B | Selectivity index, ratio of IC50 for inhibition of PI3Kalpha (unknown origin) to IC50 for inhibition of PI3Kdelta (unknown origin) by ADP Glo luminescent assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
11. | ALA5244122 | B | Selectivity index, ratio of IC50 for inhibition of PI3Kbeta (unknown origin) to IC50 for inhibition of PI3Kdelta (unknown origin) by ADP Glo luminescent assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
12. | ALA5244123 | B | Selectivity index, ratio of IC50 for inhibition of PI3Kgamma (unknown origin) to IC50 for inhibition of PI3Kdelta (unknown origin) by ADP Glo luminescent assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
13. | ALA5244124 | F | Induction of apoptosis in human MV4-11 cells assessed as viable cells at 1 uM incubated for 48 hrs by Annexin V/PI staining based flow cytometric analysis (Rvb = 85.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA5244125 | F | Induction of apoptosis in human MV4-11 cells assessed as early apoptotic cells at 1 uM incubated for 48 hrs by Annexin V/PI staining based flow cytometric analysis (Rvb = 1.57%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA5244126 | F | Induction of apoptosis in human MV4-11 cells assessed as late apoptotic cells at 1 uM incubated for 48 hrs by Annexin V/PI staining based flow cytometric analysis (Rvb = 2.82%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA5244127 | F | Induction of apoptosis in human MV4-11 cells assessed as necrotic cells at 1 uM incubated for 48 hrs by Annexin V/PI staining based flow cytometric analysis (Rvb = 0.060%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA5244128 | F | Induction of apoptosis in human MV4-11 cells assessed as viable cells at 3 uM incubated for 48 hrs by Annexin V/PI staining based flow cytometric analysis (Rvb = 85.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA5244129 | F | Induction of apoptosis in human MV4-11 cells assessed as early apoptotic cells at 3 uM incubated for 48 hrs by Annexin V/PI staining based flow cytometric analysis (Rvb = 1.57%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA5244130 | F | Induction of apoptosis in human MV4-11 cells assessed as late apoptotic cells at 3 uM incubated for 48 hrs by Annexin V/PI staining based flow cytometric analysis (Rvb = 2.82%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA5244131 | F | Induction of apoptosis in human MV4-11 cells assessed as necrotic cells at 3 uM incubated for 48 hrs by Annexin V/PI staining based flow cytometric analysis (Rvb = 0.060%) | Homo sapiens | 1 | cell-based format | Scientific Literature |