| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5250298 | F | Antiproliferative activity against human AGS cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 2. | ALA5250299 | F | Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 3. | ALA5250300 | A | Metabolic stability in human liver microsomes assessed as clearance | Homo sapiens | 12 | microsome format | Scientific Literature | ||
| 4. | ALA5250301 | A | Metabolic stability in human liver microsomes assessed as half life | Homo sapiens | 12 | microsome format | Scientific Literature | ||
| 5. | ALA5250302 | B | Inhibition of STAT3 (unknown origin) transcriptional signaling transfected in HEK293T cells at 3 uM incubated for 24 hrs by firefly luciferase gene reporter assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 6. | ALA5250303 | B | Thermal stabilization of STAT3 in human AGS cells at 1 uM at 37 to 54 degreeC incubated for 1 hr by cellular thermal shift assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA5250304 | B | Inhibition of STAT3 in human AGS cells assessed as inhibition of STAT3 phosphorylation level at Tyr705 at 0.3 to 3 uM by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5250305 | B | Inhibition of STAT3 in human MGC-803 cells assessed as inhibition of STAT3 phosphorylation level at Tyr705 at 0.3 to 3 uM by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5250306 | B | Inhibition of STAT3 in human AGS cells assessed as inhibition of total STAT3 protein level at 0.3 to 3 uM by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5250307 | B | Inhibition of STAT3 in human MGC-803 cells assessed as inhibition of total STAT3 protein level at 0.3 to 3 uM by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5250308 | B | Inhibition of STAT1 in human AGS cells assessed as inhibition of STAT1 phosphorylation level at Tyr701 at 0.3 to 3 uM by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5250309 | B | Inhibition of HA-tagged STAT3 (unknown origin) dimerization transfected in HEK293T cells at 0.3 to 3 uM incubated for 24 hrs followed by IL-6 stimulation and measured after 1 hr by immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5250310 | B | Inhibition of Flag-tagged STAT3 (unknown origin) dimerization transfected in HEK293T cells at 0.3 to 3 uM incubated for 24 hrs followed by IL-6 stimulation and measured after 1 hr by immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5250311 | B | Inhibition of STAT3 in human AGS cells assessed as reduction of c-Myc protein expression level at 0.3 to 3 uM by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5250312 | B | Inhibition of STAT3 in human AGS cells assessed as reduction of Mcl-1 protein expression level at 0.3 to 3 uM by western blot assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5250313 | F | Inhibition of colony formation in human AGS cells at 0.3 to 3 uM incubated for 10 to 15 days by crystal violet staining based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA5250314 | F | Inhibition of colony formation in human MGC-803 cells at 0.3 to 3 uM incubated for 10 to 15 days by crystal violet staining based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA5250315 | F | Induction of apoptosis in human AGS cells assessed as viable cells at 0.3 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry method (Rvb = 94.8 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA5250316 | F | Induction of apoptosis in human AGS cells assessed as viable cells at 1 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry method (Rvb = 94.8 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA5250317 | F | Induction of apoptosis in human AGS cells assessed as viable cells at 3 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry method (Rvb = 94.8 %) | Homo sapiens | 2 | cell-based format | Scientific Literature |
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