| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5252950 | B | Binding affinity to HIV1 protease assessed as inhibition constant | Human immunodeficiency virus 1 | 20 | single protein format | Scientific Literature | ||
| 2. | ALA5252951 | F | Antiviral activity against HIV1 LAI infected in human MT2 cells assessed as inhibition of virus-induced cytopathic effect by MTT assay | Human immunodeficiency virus 1 | 5 | organism-based format | Scientific Literature | ||
| 3. | ALA5252952 | F | Antiviral activity against wild type HIV1 ERS104pre infected in human PBMC cells assessed as inhibition of virus-induced cytopathic effect measured after 7 days by MTT assay | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
| 4. | ALA5252953 | F | Antiviral activity against multidrug-resistant HIV1-TM infected in phytohemagglutinin-activated human PBMC cells assessed as inhibition of virus-induced cytopathic effect measured after 7 days by MTT assay | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
| 5. | ALA5252954 | F | Antiviral activity against multidrug-resistant HIV1-MM infected in phytohemagglutinin-activated human PBMC cells assessed as inhibition of virus-induced cytopathic effect measured after 7 days by MTT assay | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
| 6. | ALA5252955 | F | Antiviral activity against multidrug-resistant HIV1-JSL infected in phytohemagglutinin-activated human PBMC cells assessed as inhibition of virus-induced cytopathic effect measured after 7 days by MTT assay | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
| 7. | ALA5252956 | F | Antiviral activity against multidrug-resistant HIV1-B infected in phytohemagglutinin-activated human PBMC cells assessed as inhibition of virus-induced cytopathic effect measured after 7 days by MTT assay | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
| 8. | ALA5252957 | F | Antiviral activity against multidrug-resistant HIV1-C infected in phytohemagglutinin-activated human PBMC cells assessed as inhibition of virus-induced cytopathic effect measured after 7 days by MTT assay | Human immunodeficiency virus 1 | 11 | organism-based format | Scientific Literature | ||
| 9. | ALA5252958 | F | Antiviral activity against multidrug-resistant HIV1-G infected in phytohemagglutinin-activated human PBMC cells assessed as inhibition of virus-induced cytopathic effect measured after 7 days by MTT assay | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
| 10. | ALA5252959 | F | Ratio of EC50 for antiviral activity against HIV1-TM to EC50 for antiviral activity against wild type HIV1 ERS104pre | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
| 11. | ALA5252960 | F | Ratio of EC50 for antiviral activity against HIV1-MM to EC50 for antiviral activity against wild type HIV1 ERS104pre | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
| 12. | ALA5252961 | F | Ratio of EC50 for antiviral activity against HIV1-JSL to EC50 for antiviral activity against wild type HIV1 ERS104pre | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
| 13. | ALA5252962 | F | Ratio of EC50 for antiviral activity against HIV1-B to EC50 for antiviral activity against wild type HIV1 ERS104pre | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
| 14. | ALA5252963 | F | Ratio of EC50 for antiviral activity against HIV1-C to EC50 for antiviral activity against wild type HIV1 ERS104pre | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
| 15. | ALA5252964 | F | Ratio of EC50 for antiviral activity against HIV1-G to EC50 for antiviral activity against wild type HIV1 ERS104pre | Human immunodeficiency virus 1 | 10 | organism-based format | Scientific Literature | ||
| 16. | ALA5252980 | T | Cytotoxicity against human MT2 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA5252981 | T | Selectivity index, ratio of CC50 for human MT2 cells to IC50 for antiviral activity against HIV1 LAI | 2 | assay format | Scientific Literature | |||
| 18. | ALA5252982 | P | Lipophilicity, logP of the compound in Octanol/water by shake-flask method | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 19. | ALA5252983 | P | Lipophilicity, logD of the compound in Octanol/buffer by shake-flask method | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 20. | ALA5252985 | A | Apparent permeability in rat astrocytes/rat pericytes/monkey endothelial cells triple cell co-culture system incubated for 30 mins by spectrophotometric analysis | 3 | cell-based format | Scientific Literature |
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