| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5248786 | F | Antiinflammatory activity against LPS-injured mouse BV-2 cells assessed as decrease in IL-1beta level at 5 uM by immunofluorescence staining based analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA5248787 | B | Inhibition of electric eel AChE using ATC and BTC iodide as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by DTNB reagent based assay | Electrophorus electricus | 31 | single protein format | Scientific Literature | ||
| 3. | ALA5248788 | B | Inhibition of equine serum BuChE using ATC and BTC iodide as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by DTNB reagent based assay | Equus caballus | 30 | single protein format | Scientific Literature | ||
| 4. | ALA5248789 | B | Inhibition of human AChE using ATC and BTC iodide as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by DTNB reagent based assay | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 5. | ALA5248790 | B | Non-competitive inhibition of human AChE assessed as decrease in substrate Vmax with constant Km by Lineweaver-Burk plot analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA5248791 | F | Cytotoxicity against human HepG2-ARE-C8 cells assessed as reduction in cell viability at 5 and 20 uM measured for 24 hrs by MTT assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 7. | ALA5248793 | T | Hepatotoxicity in rat PC12 cells assessed as effect on AST level | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5248794 | T | Hepatotoxicity in rat PC12 cells assessed as effect on ALT level | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5248795 | T | Hepatotoxicity in rat PC12 cells assessed as morphological changes | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5248796 | T | Cytotoxicity against rat PC12 cells assessed as growth inhibition at 5 uM after 24 hrs by MTT assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5248797 | B | Activation of Nrf2 pathway in rat PC-12 cells assessed as increase in NQO1 level at 20 uM measured after 6 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5248798 | B | Activation of Nrf2 pathway in rat PC-12 cells assessed as increase in HO-1 level at 20 uM measured after 6 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5248799 | B | Activation of Nrf2 pathway in rat PC-12 cells assessed as increase in GCLM level at 20 uM measured after 6 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5248800 | B | Induction of Nrf2 pathway in rat PC12 cells assessed as fold increase in Nrf2 level at 20 uM measured after 6 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5248801 | B | Activation of Nrf2 pathway in rat PC-12 cells assessed as fold increase in Nrf2 level at 20 uM measured at 2 hrs by qRT-PCR analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5248802 | B | Activation of Nrf2 pathway in rat PC-12 cells assessed as fold increase in HO-1 level at 20 uM measured at 2 hrs by qRT-PCR analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5248803 | B | Activation of Nrf2 pathway in rat PC-12 cells assessed as fold increase in NQO1 level at 20 uM measured at 2 hrs by qRT-PCR analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5248804 | B | Activation of Nrf2 pathway in rat PC-12 cells assessed as fold increase in GCLM level at 20 uM measured at 2 hrs by qRT-PCR analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5248805 | B | Activation of Nrf2 pathway in rat PC-12 cells assessed as fold increase in Nrf2 expression level at 1 to 20 uM measured at 6 hrs by qRT-PCR analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5248806 | B | Activation of Nrf2 pathway in rat PC-12 cells assessed as fold increase in HO-1 expression level at 1 to 20 uM measured at 6 hrs by qRT-PCR analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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