# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5236414 | B | Binding affinity to human PCSK9 | Homo sapiens | 8 | ALA5233285 | single protein format | Scientific Literature | |
2. | ALA5236424 | B | Inhibition of PCSK9-LDLR (unknown origin) protein-protein interaction | Homo sapiens | 9 | ALA5233285 | protein format | Scientific Literature | |
3. | ALA5236435 | B | Binding affinity to mouse PCSK9 | Mus musculus | 2 | ALA5233285 | single protein format | Scientific Literature | |
4. | ALA5236436 | B | Inhibition of PCSK9-LDLR (unknown origin) protein-protein interaction relative to control | Homo sapiens | 1 | ALA5233285 | protein format | Scientific Literature | |
5. | ALA5236437 | B | Inhibition of PCSK9-LDLR protein-protein interaction in human HepG2 cells assessed as increase in LDL uptake | Homo sapiens | 3 | ALA5233285 | cell-based format | Scientific Literature | |
6. | ALA5236438 | B | Inhibition of PCSK9-LDLR protein-protein interaction in human HepG2 cells assessed as increase in LDL uptake relative to control | Homo sapiens | 2 | ALA5233285 | cell-based format | Scientific Literature | |
7. | ALA5236439 | F | Hypocholesterolemic activity in C57BL/6 mouse assessed as increase in LDLR level at 30 mg/kg | Mus musculus | 1 | ALA5233285 | organism-based format | Scientific Literature | |
8. | ALA5236440 | F | Hypocholesterolemic activity in C57BL/6 mouse assessed as reduction in TC level at 30 mg/kg | Mus musculus | 1 | ALA5233285 | organism-based format | Scientific Literature |