# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5252473 | B | Inhibition of full-length human DNMT2 expressed in bacteria using tRNA-Asp as substrate and 3H-SAM as cosubstrate by tritium incorporation assay | Homo sapiens | 29 | assay format | Scientific Literature | ||
2. | ALA5252475 | B | Displacement of FTAD from full-length human DNMT2 expressed in bacteria at 20 uM incubated for 10 mins by MST assay relative to control | Homo sapiens | 30 | assay format | Scientific Literature | ||
3. | ALA5252477 | B | Displacement of FTAD from full-length human DNMT2 expressed in bacteria incubated for 10 mins by MST assay | Homo sapiens | 29 | assay format | Scientific Literature | ||
4. | ALA5252478 | B | Binding affinity to full-length human DNMT2 expressed in bacteria assessed as apparent dissociation constant by ITC method | Homo sapiens | 29 | assay format | Scientific Literature | ||
5. | ALA5252479 | B | Inhibition of full-length human DNMT2 expressed in bacteria using tRNA-Asp as substrate and [3H[-SAM as cosubstrate at 100 uM by tritium incorporation assay relative to control | Homo sapiens | 29 | assay format | Scientific Literature | ||
6. | ALA5252485 | B | Binding affinity to human DNMT2 deletion mutant expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells incubated for 1 hr under denaturing condition by protein mass spectrometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA5252486 | B | Inhibition of full-length human NSUN2 expressed in Escherichia coli Rosetta (DE3) pLysS cells at 100 uM by tritium incorporation assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
8. | ALA5252487 | B | Inhibition of full-length human NSUN6 expressed in Escherichia coli Rosetta (DE3) pLysS cells at 100 uM by tritium incorporation assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature |