# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5225149 | B | Displacement of [3H]pentazocine from sigma 1 receptor expressed in guinea pig brain membranes assessed as inhibition constant by radioligand binding assay | Cavia porcellus | 11 | ALA5223132 | cell membrane format | Scientific Literature | |
2. | ALA5225150 | B | Displacement of [3H]DTG from sigma 2 receptor expressed in rat liver membranes assessed as inhibition constant in presence of (+)-pentazocine by radioligand binding assay | Rattus norvegicus | 10 | ALA5223132 | cell membrane format | Scientific Literature | |
3. | ALA5225151 | B | Inhibition of P-gp transporter (unknown origin) expressed in dog MDCK-MDR1 assessed as inhibition of fluorescent Calcein-AM transport by fluorescence based assay | Homo sapiens | 2 | ALA5223132 | cell-based format | Scientific Literature | |
4. | ALA5225152 | F | Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 2 | ALA5223132 | cell-based format | Scientific Literature | |
5. | ALA5225153 | F | Antiproliferative activity against human SK-N-SH cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 2 | ALA5223132 | cell-based format | Scientific Literature | |
6. | ALA5225154 | F | Anticancer against dog MDCK-MDR1 cells assessed as reduction in cell viability at 50 uM incubated for 48 hrs by MTT assay | Canis lupus familiaris | 1 | ALA5223132 | cell-based format | Scientific Literature | |
7. | ALA5225155 | F | Anticancer against dog MDCK-MDR1 cells assessed as reduction in cell viability at 30 uM incubated for 48 hrs in presence of doxorubicin by MTT assay | Canis lupus familiaris | 1 | ALA5223132 | cell-based format | Scientific Literature | |
8. | ALA5225156 | F | Anticancer against dog MDCK-MDR1 cells assessed as reduction in cell viability at 50 uM incubated for 48 hrs in presence of doxorubicin by MTT assay | Canis lupus familiaris | 1 | ALA5223132 | cell-based format | Scientific Literature |